form
solid
Quality Level
SMILES string
O=NN1CCOCC1
InChI
1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2
InChI key
ZKXDGKXYMTYWTB-UHFFFAOYSA-N
Biochem/physiol Actions
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.
Packaging
散装
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
target_organs
Liver
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Muta. 2 - STOT RE 1
商品
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
W Lijinsky et al.
Carcinogenesis, 3(8), 911-915 (1982-01-01)
A comparison was made of the carcinogenic effectiveness of some cyclic nitrosamines containing oxygen in the ring. The compounds were administered to F344 rats at approximately equimolar concentrations in drinking water. Nitrosomorpholine, nitroso-1,3-oxazolidine and nitrosotetrahydro-1,3-oxazine were of similar potency and
W Lijinsky et al.
In vivo (Athens, Greece), 5(2), 85-89 (1991-03-01)
A number of nitrosamines that have been studied by administration to rats as solutions in drinking water have been examined by gavage administration of similar doses, for assessment of the role of pharmacokinetics in organ-specific carcinogenesis. Methylnitrosoethylamine was more effective
Jutta Groos et al.
Mathematical biosciences, 202(2), 248-268 (2006-04-11)
Several hypotheses are established to describe the formation and progression of foci of altered hepatocytes (FAH). A common model of hepatocarcinogenesis is the mutation model (MM), which is based on the assumption that cells have to undergo multiple successive changes
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| N7382-5ML | 04061837841224 |
| N7382-1ML | 04061834117995 |