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N7389

3-硝基-L-酪氨酸

Name: 3-硝基-<SC>L</SC>-酪氨酸
Brand: SIGMA

Oxidant, crystalline

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关于此项目

线性分子式:

O₂NC₆H₃-4-(OH)CH₂CH(NH₂)CO₂H

化学文摘社编号:

621-44-3

分子量:

226.19

NACRES:

NA.32

PubChem Substance ID:

24897825

eCl@ss:

32160406

UNSPSC Code:

12352200

EC Number:

210-688-6

MDL number:

MFCD00007123

Beilstein/REAXYS Number:

2813157

Form:

crystalline

Quality level:

200

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产品名称

3-硝基-L-酪氨酸, crystalline

form

crystalline

Quality Level

200

mp

233-235 °C (dec.) (lit.)

SMILES string

N[C@@H](Cc1ccc(O)c(c1)[N+]([O-])=O)C(O)=O

InChI

1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

FBTSQILOGYXGMD-LURJTMIESA-N

Application

3-硝基-L-酪氨酸已用于：

蛋白质印迹分析，定量分析小鼠组织蛋白中的硝基酪氨酸水平
Murashige–Skoog培养基，用于处理野生型和丝裂原活化蛋白激酶6 (mpk6)-2突变体幼苗，推断一氧化氮(NO)和MPK6在调节有丝分裂微管组织中的功能联系
免疫细胞化学

Biochem/physiol Actions

3-硝基-L-酪氨酸是一种氧化剂和细胞毒剂。在全身性自免疫疾病患者体内，3-硝基酪氨酸可作为氮自由基改性蛋白质的生物标记物。它是过氧亚硝酸盐介导的氧化损伤的标志物。硝基酪氨酸与乳腺癌患者体内的VEGF-C表达和淋巴结转移有关。3-硝基酪氨酸由氧化/亚硝化压力介导的化学改性（如在肺癌发生中观测到的蛋白质硝化）产生。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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全球贸易项目编号

货号	GTIN
N7389-25G	04061833631157
N7389-5G	04061834118008
N7389-10G	04061833631140

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