N7627
L -正缬氨酸
≥99% (TLC)
别名:
( S )-(+)-2-氨基戊酸, ( S )-2-氨基戊酸
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关于此项目
线性分子式:
CH3CH2CH2CH(NH2)CO2H
化学文摘社编号:
分子量:
117.15
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
229-543-3
MDL number:
Beilstein/REAXYS Number:
1721162
产品名称
L -正缬氨酸, arginase inhibitor
InChI key
SNDPXSYFESPGGJ-BYPYZUCNSA-N
InChI
1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
SMILES string
CCC[C@H](N)C(O)=O
assay
≥99% (TLC)
form
powder
color
white
mp
>300 °C (lit.)
application(s)
detection
Quality Level
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Application
- 纳米药物介导TAM相关精氨酸代谢干扰，促进光动力免疫治疗。：该研究探讨了使用纳米药物干扰肿瘤相关巨噬细胞（TAM）的精氨酸代谢，增强光动力免疫治疗的疗效。L-正缬氨酸在这种代谢干扰中起着至关重要的作用（Chen et al., 2024）。
Biochem/physiol Actions
L-正缬氨酸增强活化巨噬细胞产生 NO。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Hany M El-Bassossy et al.
Vascular pharmacology, 57(5-6), 194-200 (2012-01-28)
Increased arginase activity has been reported in a variety of disease conditions characterized by vascular dysfunction. In the present study, the potentially protective effect of arginase inhibition against the hypertension associated with diabetes has been investigated. Diabetes was induced by
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