N7627
L -正缬氨酸
≥99% (TLC)
别名:
( S )-(+)-2-氨基戊酸, ( S )-2-氨基戊酸
产品名称
L -正缬氨酸, arginase inhibitor
质量水平
方案
≥99% (TLC)
表单
powder
颜色
white
mp
>300 °C (lit.)
应用
detection
SMILES字符串
CCC[C@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key
SNDPXSYFESPGGJ-BYPYZUCNSA-N
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应用
- 纳米药物介导TAM相关精氨酸代谢干扰，促进光动力免疫治疗。：该研究探讨了使用纳米药物干扰肿瘤相关巨噬细胞（TAM）的精氨酸代谢，增强光动力免疫治疗的疗效。L-正缬氨酸在这种代谢干扰中起着至关重要的作用（Chen et al., 2024）。
生化/生理作用
L-正缬氨酸增强活化巨噬细胞产生 NO。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Mark R Sullivan et al.
Cell metabolism, 29(6), 1410-1421 (2019-03-25)
Tumors exhibit altered metabolism compared to normal tissues. Many cancers upregulate expression of serine synthesis pathway enzymes, and some tumors exhibit copy-number gain of the gene encoding the first enzyme in the pathway, phosphoglycerate dehydrogenase (PHGDH). However, whether increased serine
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