N7627
L -正缬氨酸
≥99% (TLC)
别名:
( S )-(+)-2-氨基戊酸, ( S )-2-氨基戊酸
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关于此项目
线性分子式:
CH3CH2CH2CH(NH2)CO2H
化学文摘社编号:
分子量:
117.15
Beilstein:
1721162
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
产品名称
L -正缬氨酸, arginase inhibitor
方案
≥99% (TLC)
表单
powder
颜色
white
mp
>300 °C (lit.)
应用
detection
SMILES字符串
CCC[C@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key
SNDPXSYFESPGGJ-BYPYZUCNSA-N
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应用
- 纳米药物介导TAM相关精氨酸代谢干扰，促进光动力免疫治疗。：该研究探讨了使用纳米药物干扰肿瘤相关巨噬细胞（TAM）的精氨酸代谢，增强光动力免疫治疗的疗效。L-正缬氨酸在这种代谢干扰中起着至关重要的作用（Chen et al., 2024）。
生化/生理作用
L-正缬氨酸增强活化巨噬细胞产生 NO。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
Mark R Sullivan et al.
Cell metabolism, 29(6), 1410-1421 (2019-03-25)
Tumors exhibit altered metabolism compared to normal tissues. Many cancers upregulate expression of serine synthesis pathway enzymes, and some tumors exhibit copy-number gain of the gene encoding the first enzyme in the pathway, phosphoglycerate dehydrogenase (PHGDH). However, whether increased serine
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