质量水平
方案
≥98%
表单
powder
溶解性
DMF: 50 mg/mL, clear, yellow to orange
储存温度
−20°C
SMILES字符串
[O-][N+](=O)c1cccc2cn[nH]c12
InChI
1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)
InChI key
PQCAUHUKTBHUSA-UHFFFAOYSA-N
基因信息
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
rat ... Nos1(24598)
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相关类别
警示用语:
Danger
危险分类
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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J Garthwaite
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Experimental neurology, 239, 111-119 (2012-10-16)
We have previously shown that intrathecal administration of the adrenomedullin (AM) receptor antagonist AM(22-52) produces a long-lasting anti-hyperalgesia effect. This study examined the hypothesis that AM recruits other pronociceptive mediators in complete Freund's adjuvant (CFA)-induced inflammation. Injection of CFA in
Geoffrey E Ciarlone et al.
American journal of physiology. Cell physiology, 311(6), C1014-C1026 (2016-10-14)
Central CO2-chemosensitive neurons in the caudal solitary complex (cSC) are stimulated not only by hypercapnic acidosis, but by hyperoxia as well. While a cellular mechanism for the CO2 response has yet to be isolated, previous data show that a redox-sensitive
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