N7778
7-硝基吲唑
≥98%
别名:
7-NI
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关于此项目
经验公式（希尔记法）:
C7H5N3O2
化学文摘社编号:
分子量:
163.13
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
220-934-4
MDL number:
产品名称
7-硝基吲唑, ≥98%
InChI key
PQCAUHUKTBHUSA-UHFFFAOYSA-N
InChI
1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)
SMILES string
[O-][N+](=O)c1cccc2cn[nH]c12
assay
≥98%
form
powder
solubility
DMF: 50 mg/mL, clear, yellow to orange
storage temp.
−20°C
Quality Level
Gene Information
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
rat ... Nos1(24598)
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相关类别
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Experimental neurology, 239, 111-119 (2012-10-16)
We have previously shown that intrathecal administration of the adrenomedullin (AM) receptor antagonist AM(22-52) produces a long-lasting anti-hyperalgesia effect. This study examined the hypothesis that AM recruits other pronociceptive mediators in complete Freund's adjuvant (CFA)-induced inflammation. Injection of CFA in
Philippe Bonnin et al.
International journal of molecular sciences, 21(18) (2020-09-12)
The poly(ADP-ribose) polymerase (PARP) inhibitor PJ34 has been reported to improve endothelial dysfunction in the peripheral system. We addressed the role of PJ34 on the vascular tone and vasoreactivity during development in the mouse brain. Blood flows were measured in
J Garthwaite
Trends in neurosciences, 14(2), 60-67 (1991-02-01)
Nitric oxide (NO) is a recently discovered and highly unorthodox messenger molecule. Current evidence indicates that, in the CNS, NO is produced enzymatically in postsynaptic structures in response to activation of excitatory amino acid receptors. It then diffuses out to
Chong Zhe Pei et al.
Stem cell research & therapy, 11(1), 28-28 (2020-01-23)
Endothelial progenitor cells (EPCs) contribute to reendothelialization and neovascularization and protect against vascular injury and ischemia of various organs. We have previously shown downregulation of microRNA (miR)-126 in EPCs from diabetic patients, which contributes to dysfunction of EPCs including impaired
Xinjian Zhu et al.
Frontiers in cellular neuroscience, 11, 377-377 (2017-12-14)
Epilepsy is one of the most common chronic neurological disorders which provoke progressive neuronal degeneration. Endoplasmic reticulum (ER) stress has recently been recognized as pivotal etiological factors contributing to epilepsy-induced neuronal damage. However, the specific contribution of epilepsy made to
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