N8130
4-硝基苯基乙酸酯
esterase substrate, chromogenic, ≥98% (TLC), powder or crystals
别名:
乙酸4-硝基苯酯
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关于此项目
线性分子式:
CH3CO2C6H4NO2
化学文摘社编号:
分子量:
181.15
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
212-593-5
MDL number:
Beilstein/REAXYS Number:
515874
产品名称
4-硝基苯基乙酸酯, esterase substrate
InChI key
QAUUDNIGJSLPSX-UHFFFAOYSA-N
InChI
1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
SMILES string
CC(=O)Oc1ccc(cc1)[N+]([O-])=O
assay
≥98% (TLC)
form
powder or crystals
mp
75-77 °C (lit.)
storage temp.
−20°C
Quality Level
Gene Information
human ... PON1(5444)
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Application
4-硝基苯基乙酸酯已用于：
- 评估人胚肾细胞系中的酯酶活性
- 碳酸酐酶抑制试验
- 通过牛血清白蛋白的酯酶活性，将其转换为 对硝基苯酚（p-NP）的研究中
- 作为确定小鼠肝细胞中羧酸酯酶（CES）活性的底物
- 研究磁性CLEAs基质中交联酶聚集体（CLEAs）和磁性氧化铁纳米粒子（MIONPs）的生物共轭优势
General description
生色酯酶底物。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
存储类别
5.1B - Oxidizing hazardous materials
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves, type N95 (US)
Impact of diet on irinotecan toxicity in mice
Mallick P, et al.
Chemico-Biological Interactions, 291, 87-94 (2018)
Beyond esterase-like activity of serum albumin. Histidine-(nitro) phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light
Kowacz M and Warszynski P
arXiv (2018)
Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae
Afzal K, et al.
Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)
Michelle R Baker et al.
Biochemistry research international, 2011, 739712-739712 (2011-09-16)
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and
Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
Emmanuel Vázquez-Mayorga et al.
International journal of molecular sciences, 17(8) (2016-08-25)
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both
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