N8133
Nerve Growth Factor from Vipera lebetina venom
lyophilized powder, suitable for cell culture
别名:
NGF
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关于此项目
Biological source:
Vipera Lebetina
Form:
lyophilized powder
Mol wt:
protein 32.5 kDa
Impurities:
<10 EU/vial
产品名称
Nerve Growth Factor from Vipera lebetina venom, NGF, lyophilized powder, suitable for cell culture
biological source
Vipera Lebetina
form
lyophilized powder
potency
0.2-20 μg/mL ED50/EC50
quality
endotoxin tested
mol wt
protein 32.5 kDa
packaging
pkg of 0.1 mg
technique(s)
cell culture | mammalian: suitable
impurities
<10 EU/vial
color
white to off-white
UniProt accession no.
storage temp.
−20°C
Quality Level
Physical form
Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.
Preparation Note
Isolated from the snake venom of V. lebetina.
Analysis Note
The biological activity of Nerve Growth Factor (NGF) from Vipera lebetina venom is measured in a cell proliferation assay using PC-12 cells.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Lucy Hepburn et al.
Science (New York, N.Y.), 346(6209), 641-646 (2014-11-02)
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent. We have found that the structurally related cystine-knot protein, nerve growth factor
Giusi Prencipe et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 3345-3354 (2014-03-04)
Nerve growth factor (NGF) levels are highly increased in inflamed tissues, but their role is unclear. We show that NGF is part of a regulatory loop in monocytes: inflammatory stimuli, while activating a proinflammatory response through TLRs, upregulate the expression
Rachel T Uren et al.
Journal of neurochemistry, 129(4), 614-627 (2014-02-04)
Suppressor of cytokine signaling-2 (SOCS2) is a regulator of intracellular responses to growth factors and cytokines. Cultured dorsal root ganglia neurons from neonatal mice with increased or decreased SOCS2 expression were examined for altered responsiveness to nerve growth factor (NGF).
Tao Yu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6098-6106 (2014-04-25)
Trk neurotrophin receptor ubiquitination in response to ligand activation regulates signaling, trafficking, and degradation of the receptors. However, the in vivo consequences of Trk ubiquitination remain to be addressed. We have developed a mouse model with a mutation in the
M Florencia Iulita et al.
Trends in pharmacological sciences, 35(7), 338-348 (2014-06-26)
Alzheimer's disease (AD) is a devastating neurodegenerative condition and the most common type of amnestic dementia in the elderly. Individuals with Down syndrome (DS) are at increased risk of developing AD in adulthood as a result of chromosome 21 trisomy
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