产品名称
Nerve Growth Factor from Vipera lebetina venom, NGF, lyophilized powder, suitable for cell culture
生物来源
Vipera Lebetina
质量水平
表单
lyophilized powder
效能
0.2-20 μg/mL ED50/EC50
质量
endotoxin tested
分子量
protein 32.5 kDa
包装
pkg of 0.1 mg
技术
cell culture | mammalian: suitable
杂质
<10 EU/vial
颜色
white to off-white
UniProt登记号
储存温度
−20°C
外形
Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.
制备说明
Isolated from the snake venom of V. lebetina.
分析说明
The biological activity of Nerve Growth Factor (NGF) from Vipera lebetina venom is measured in a cell proliferation assay using PC-12 cells.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Lucy Hepburn et al.
Science (New York, N.Y.), 346(6209), 641-646 (2014-11-02)
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent. We have found that the structurally related cystine-knot protein, nerve growth factor
Giusi Prencipe et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 3345-3354 (2014-03-04)
Nerve growth factor (NGF) levels are highly increased in inflamed tissues, but their role is unclear. We show that NGF is part of a regulatory loop in monocytes: inflammatory stimuli, while activating a proinflammatory response through TLRs, upregulate the expression
M Florencia Iulita et al.
Trends in pharmacological sciences, 35(7), 338-348 (2014-06-26)
Alzheimer's disease (AD) is a devastating neurodegenerative condition and the most common type of amnestic dementia in the elderly. Individuals with Down syndrome (DS) are at increased risk of developing AD in adulthood as a result of chromosome 21 trisomy
Geraldine Longo et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(24), 10066-10074 (2013-06-14)
Although chronic pain is the most common symptom of arthritis, relatively little is known about the mechanisms driving it. Recently, a sprouting of autonomic sympathetic fibers into the upper dermis of the skin, an area that is normally devoid of
Tao Yu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6098-6106 (2014-04-25)
Trk neurotrophin receptor ubiquitination in response to ligand activation regulates signaling, trafficking, and degradation of the receptors. However, the in vivo consequences of Trk ubiquitination remain to be addressed. We have developed a mouse model with a mutation in the
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