N8912
Monoclonal Anti-NG2 antibody produced in mouse
clone 132.38, purified immunoglobulin, buffered aqueous solution
别名:
Anti-Chondroitin Sulfate Proteoglycan Melanoma-associated, Anti-MCSP, Anti-MCSPG, Anti-MEL-CSPG MSK16 Chondroitin Sulfate Proteoglycan NG2
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关于此项目
Conjugate:
unconjugated
Clone:
132.38, monoclonal
Application:
ARR, ELISA (i), ICC, IP, WB
Citations:
9
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
132.38, monoclonal
form
buffered aqueous solution
species reactivity
rat
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, microarray: suitable, western blot: 1 μg/mL using rat brain neonatal extract
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Cspg4(81651)
General description
Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) is a growth-inhibitory chondroitin sulfate proteoglycan (CSPG) produced after spinal cord injury. It has a single glycosaminoglycan (GAG) chain. The protein belongs to the transmembrane chondroitin sulfate proteoglycans family.
Immunogen
cell extract of HEK293 cells expressing the D3 domain of rat NG2.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting
Immunohistochemistry (1 paper)
Western Blotting
Biochem/physiol Actions
Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) stimulates the activation of integrins in dorsal root ganglion neurons. It also has a role in stimulating inflammatory cytokine expression in microglia.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)