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About This Item
经验公式（希尔记法）:
C18H26N10O3 · 2HCl
CAS Number:
分子量:
503.39
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
生物来源
Streptomyces netropsis
质量水平
方案
≥98% (HPLC and TLC)
表单
powder
颜色
faintly yellow
溶解性
H2O: 1 mg/mL
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
viruses
作用机制
DNA synthesis | interferes
储存温度
−20°C
SMILES字符串
[H]Cl.[H]Cl.NC(CCNC(C1=CC(NC(C2=CC(NC(CNC(N)=N)=O)=CN2C)=O)=CN1C)=O)=N
InChI
1S/C18H26N10O3.2ClH/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22;;/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24);2*1H
InChI key
SDRHUASONSRLFR-UHFFFAOYSA-N
生化/生理作用
Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.
注意
Protect from light.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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