O1764
N-(3-氧代辛酰基)-L-高丝氨酸内酯
≥97% (HPLC), white, powder
别名:
3-oxo-C8-HSL, 3OC8-HSL, N-(β-酮辛酰基)-L-高丝氨酸
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关于此项目
经验公式（希尔记法）:
C12H19NO4
化学文摘社编号:
分子量:
241.28
MDL编号:
UNSPSC代码:
12352202
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.32
质量水平
方案
≥97% (HPLC)
表单
powder
分子量
241.28
技术
protein expression: suitable
颜色
white
溶解性
chloroform: 50 mg/mL, clear, colorless
运输
wet ice
储存温度
−20°C
SMILES字符串
CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
InChI
1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
InChI key
FXCMGCFNLNFLSH-JTQLQIEISA-N
一般描述
N-（3-氧代辛酰基）-L-高丝氨酸内酯是一种常见的群体感应（QS）信号。
它是一种由革兰氏阴性菌产生的信号分子。
它是一种由革兰氏阴性菌产生的信号分子。
应用
N-（3-氧代辛酰基）-L-高丝氨酸内酯已用于：
- 研究pH、温度和盐度对假单胞菌生物膜的胞外聚合物物质（EPS）的影响。
- 作为AHL诱导剂激活长聚球藻群体感知途径。
生化/生理作用
N-（3-氧代辛酰基）-L-高丝氨酸内酯可刺激tra基因的表达。它是一种自诱导剂和强效拮抗剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
S Swift et al.
Molecular microbiology, 10(3), 511-520 (1993-11-01)
The pheromone N-(3-oxohexanoyl)-L-homoserine lactone (OHHL) regulates expression of bioluminescence in the marine bacterium Vibrio fischeri, the production of carbapenem antibiotic in Erwinia carotovora and exoenzymes in both E. carotovora and Pseudomonas aeruginosa. A characteristic feature of this regulatory mechanism in
J Zhu et al.
Journal of bacteriology, 180(20), 5398-5405 (1998-10-10)
The TraR and TraI proteins of Agrobacterium tumefaciens mediate cell-density-dependent expression of the Ti plasmid tra regulon. TraI synthesizes the autoinducer pheromone N-(3-oxooctanoyl)-L-homoserine lactone (3-oxo-C8-HSL), while TraR is an 3-oxo-C8-HSL-responsive transcriptional activator. We have compared the abilities of 3-oxo-C8-HSL and
Developing Cyanobacterial Quorum Sensing Toolkits: Toward Interspecies Coordination in Mixed Autotroph/Heterotroph Communities
Kokarakis EJ, et al.
ACS Synthetic Biology, 12(1), 265-276 (2023)
Quorum-sensing molecules: Sampling, identification and characterization of N-acyl-homoserine lactone in Vibrio sp
Laj N, et al.
Saudi Journal of Biological Sciences, 29(4), 2733-2737 (2022)
Z Q Luo et al.
The Journal of biological chemistry, 275(11), 7713-7722 (2000-03-14)
Conjugal transfer of Agrobacterium tumefaciens Ti plasmids is regulated by quorum sensing via the transcriptional activator TraR and the acyl-homoserine lactone Agrobacterium autoinducer (AAI). Unique to this system, the activity of TraR is negatively modulated by an antiactivator called TraM.
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