O3011
Oxiracetam
别名:
4-Hydroxy-2-oxopyrrolidine-N-acetamide
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关于此项目
经验公式（希尔记法）:
C6H10N2O3
化学文摘社编号:
分子量:
158.16
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
storage temp.
2-8°C
SMILES string
NC(=O)CN1CC(O)CC1=O
InChI
1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10)
InChI key
IHLAQQPQKRMGSS-UHFFFAOYSA-N
Biochem/physiol Actions
Nootropic agent, improves learning and memory, and prevents impairment of cognitive functions. Its mechanism of action in not yet known, but it is suggested to modulate glutamatergic and cholinergic neurotransmission. Protein kinase C may be involved.
Nootropic agent, improves learning and memory.
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
I N Krylov et al.
Biulleten' eksperimental'noi biologii i meditsiny, 115(3), 260-262 (1993-03-01)
Acute exposure of rats to microwaves (12.6 chr, 2375 MHz, power density 1 mW/cm2) induced the retrograde amnesia. It was show the role of opioidergic, benzodiazepine, GABAergic and cholinergic components in the amnesic effects of microwaves. Piracetam (100 mg/kg, i.
Z Hlinák et al.
European journal of pharmacology, 314(1-2), 1-7 (1996-10-24)
In the present study, the elevated plus-maze was used to evaluate memory in female mice. In Experiment 1, the mice retested on day 1, 4 or 7 after the initial session escaped from the open arm into the enclosed arm
M Pinza et al.
Journal of medicinal chemistry, 36(26), 4214-4220 (1993-12-24)
A series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones were synthesized. These bicylic derivatives contain both the 2-pyrrolidinone and 4-imidazolidinone nuclei, already recognized as important for cognition enhancing activity. In addition, these structures maintain the backbone of piracetam and oxiracetam with the acetamide side chain