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O4011

Orphanin FQ

≥95% (HPLC)

别名:

Nociceptin

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关于此项目

经验公式（希尔记法）:
C79H129N27O22
化学文摘社编号:
170713-75-4
分子量:
1809.04
NACRES:
NA.32
UNSPSC Code:
12352200
MDL number:
MFCD00677528
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assay

≥95% (HPLC)

form

powder

composition

Peptide content, ≥70%

UniProt accession no.

Q13519

storage temp.

−20°C

InChI

1S/C79H129N27O22/c1-41(2)33-54(72(122)95-44(5)66(116)103-56(36-59(84)110)73(123)102-53(77(127)128)27-28-58(83)109)104-70(120)49(23-13-15-29-80)100-69(119)52(26-18-32-90-79(87)88)99-65(115)43(4)96-75(125)57(40-107)105-71(121)50(24-14-16-30-81)101-68(118)51(25-17-31-89-78(85)86)98-64(114)42(3)94-61(112)39-93-76(126)63(45(6)108)106-74(124)55(35-47-21-11-8-12-22-47)97-62(113)38-91-60(111)37-92-67(117)48(82)34-46-19-9-7-10-20-46/h7-12,19-22,41-45,48-57,63,107-108H,13-18,23-40,80-82H2,1-6H3,(H2,83,109)(H2,84,110)(H,91,111)(H,92,117)(H,93,126)(H,94,112)(H,95,122)(H,96,125)(H,97,113)(H,98,114)(H,99,115)(H,100,119)(H,101,118)(H,102,123)(H,103,116)(H,104,120)(H,105,121)(H,106,124)(H,127,128)(H4,85,86,89)(H4,87,88,90)/t42-,43-,44-,45+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-/m0/s1

InChI key

PULGYDLMFSFVBL-SMFNREODSA-N

Gene Information

human ... PNOC(5368)

Biochem/physiol Actions

Endogenous agonist at opioid receptor-like1 (ORL1) receptors.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number
030M1863
059K1240
088K1329
027K1576
056K1672

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C T Dooley et al.
Peptides, 21(7), 949-960 (2000-09-22)
A review of the binding studies performed on the receptor (ORL) for Orphanin FQ/Nociceptin is presented. Binding studies have been conducted using a variety of receptor sources: cell lines expressing the cloned receptor, cell lines endogenously expressing the receptor, and
R K Reinscheid et al.
Science (New York, N.Y.), 270(5237), 792-794 (1995-11-03)
A heptadecapeptide was identified and purified from porcine brain tissue as a ligand for an orphan heterotrimeric GTP-binding protein (G protein)-coupled receptor (LC132) that is similar in sequence to opioid receptors. This peptide, orphanin FQ, has a primary structure reminiscent
L C Chiou
Journal of biomedical science, 7(3), 232-240 (2000-05-16)
A novel opioid receptor-like orphan receptor (ORL1) was cloned and identified to be homologous to classical opioid receptors but insensitive to traditional opioids. A heptadecapeptide, termed orphanin FQ or nociceptin (OFQ/N), was identified as its endogenous ligand. OFQ/N shares overlapping
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全球贸易项目编号

货号GTIN
O4011-1MG04061834227908