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Merck
CN

O5507

Sigma-Aldrich

共轭亚油酸

别名:

共轭亚油酸, 十八碳二烯酸,共轭

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关于此项目

UNSPSC代码:
12352211
NACRES:
NA.77
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杂质

≤1% Linoleic acid

质量水平

脂质类型

omega FAs

储存温度

−20°C

一般描述

顺式和反式-9,11-和-10,12-十八碳二烯酸的混合物。异构体比例可能因批次而异。

应用


  • A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis.:开发靶向纳米调节剂(包含共轭亚油酸)以调节肿瘤微环境并抑制转移。说明促进癌症治疗的巨大潜能(Tian et al., 2022)。

  • Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.:用共轭亚油酸-壳聚糖制备透明质酸改性纳米颗粒,以共递送miR34a和阿霉素。用于解决乳腺癌治疗中的耐药问题(Yang et al., 2022)。

生化/生理作用

乳腺、皮肤和结肠癌发生和肿瘤细胞增殖的有效抑制剂;抑制bFGF诱导的内皮细胞增殖;强效抗氧化剂。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Atique A Behan et al.
Animals : an open access journal from MDPI, 9(7) (2019-07-03)
Rumen protected fats (RPF) are known to improve animal performance without affecting rumen metabolism in sheep. However, comparative effects of prilled fat, prilled fat with lecithin and calcium soap have not been fully studied. Hence this experiment was planned using
Martha A Belury
The Journal of nutrition, 132(10), 2995-2998 (2002-10-09)
Conjugated linoleic acid (CLA) is composed of positional and stereoisomers of octadecadienoate (18:2); it is found in foods derived from ruminants (beef and lamb as well as dairy products from these sources). When a mixture of isomers is fed to
Eun-Joung Moon et al.
Oncology reports, 10(3), 617-621 (2003-04-10)
Conjugated linoleic acid (CLA) is a potent inhibitor of mammary carcinogenesis. Cancer cells produce various angiogenic factors which stimulate host vascular endothelial cell mitogenesis and chemotaxis for their growth and metastasis. Basic fibroblast growth factor (bFGF) is a potent angiogenic
Daeun Lee et al.
Archives of pharmacal research, 43(4), 449-461 (2020-04-03)
Schizophyllan (SPG), produced by Schizophyllum commune, is an exopolysaccharide with multiple academic and commercial uses, including in the food industry and for various medical functions. We previously demonstrated that SPG conjugated with c-Src peptide exerted a significant therapeutic effect on
Rui Guo et al.
Frontiers in nutrition, 9, 1026740-1026740 (2022-11-01)
Dietary fat composition is closely associated with the pathological development of alcoholic liver disease (ALD). Fat enriched with saturated fatty acids protects whereas with polyunsaturated fatty acids aggravates alcohol-induced liver injury. However, limited study has addressed how monounsaturated fatty acids

商品

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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