一般描述
顺式和反式-9,11-和-10,12-十八碳二烯酸的混合物。异构体比例可能因批次而异。
应用
- A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis.：开发靶向纳米调节剂（包含共轭亚油酸）以调节肿瘤微环境并抑制转移。说明促进癌症治疗的巨大潜能(Tian et al., 2022)。
- Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.：用共轭亚油酸-壳聚糖制备透明质酸改性纳米颗粒，以共递送miR34a和阿霉素。用于解决乳腺癌治疗中的耐药问题(Yang et al., 2022)。
生化/生理作用
乳腺、皮肤和结肠癌发生和肿瘤细胞增殖的有效抑制剂；抑制bFGF诱导的内皮细胞增殖；强效抗氧化剂。
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Swati Shivani et al.
Journal of the science of food and agriculture, 96(5), 1716-1722 (2015-05-29)
Conjugated linoleic acid (CLA) isomers have high health amelioration potential and hence it is of great interest to increase the CLA content in dairy products. The present study was conducted to investigate the effect of administration of high CLA producing
Christina Donnelly et al.
Nutrition and cancer, 61(1), 114-122 (2009-01-01)
Spot 14 (THRSP, S14) is a nuclear protein involved in the regulation of genes required for fatty acid synthesis in normal and malignant mammary epithelial and adipose cells. Harvatine and Bauman (1) reported that conjugated linoleic acid (CLA) inhibits S14
Rui Guo et al.
Frontiers in nutrition, 9, 1026740-1026740 (2022-11-01)
Dietary fat composition is closely associated with the pathological development of alcoholic liver disease (ALD). Fat enriched with saturated fatty acids protects whereas with polyunsaturated fatty acids aggravates alcohol-induced liver injury. However, limited study has addressed how monounsaturated fatty acids
Daeun Lee et al.
Archives of pharmacal research, 43(4), 449-461 (2020-04-03)
Schizophyllan (SPG), produced by Schizophyllum commune, is an exopolysaccharide with multiple academic and commercial uses, including in the food industry and for various medical functions. We previously demonstrated that SPG conjugated with c-Src peptide exerted a significant therapeutic effect on
M S Vela Gurovic et al.
Food & function, 6(11), 3437-3443 (2015-08-25)
Chitooligosaccharides (COSs) have been clinically evaluated for their immunostimulating effects after oral intake. Similar to dietary supplements, prebiotics and biopreservatives, these water-soluble bioactives are easily incorporated into dairy products and beverages. Notwithstanding, the use of COS in fermented foods would
商品
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。
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