O5636
9,12-Octadecadiynoic acid
≥98%
别名:
ODYA, Ro 3-1314
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关于此项目
经验公式（希尔记法）:
C18H28O2
化学文摘社编号:
分子量:
276.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
InChI
1S/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-5,8,11-17H2,1H3,(H,19,20)
SMILES string
CCCCCC#CCC#CCCCCCCCC(O)=O
InChI key
KDYILQLPKVZDGB-UHFFFAOYSA-N
assay
≥98%
form
crystalline
mp
45-46 °C
solubility
water: slightly soluble
shipped in
wet ice
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Potent cyclooxygenase and lipoxygenase inhibitor.
Disclaimer
Oxygen and light sensitive.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M Hitchcock et al.
British journal of pharmacology, 72(4), 689-695 (1981-04-01)
1. 5,8,11,14-Eicosatetraynoic acid (ETYA) inhibited the antigen-induced contractions of tracheal spirals obtained from actively sensitized guinea-pigs. Consistent data were obtained only when the spirals were treated with indomethacin. 2. ETYA did not affect histamine-induced contractions of indomethacin-treated tracheal spirals. 3.
Ning Wang et al.
Frontiers in physiology, 9, 583-583 (2018-06-08)
Background: Perivascular adipose tissue (PVAT) exerts anti-contractile effects on visceral arteries by release of various perivascular relaxing factors (PVRFs) and opening voltage-gated K+ (Kv) channels in vascular smooth muscle cells (VSMCs). Palmitic acid methyl ester (PAME) has been proposed as
David R Colquhoun et al.
Proteomics, 15(12), 2066-2077 (2015-04-29)
Protein acylation plays a critical role in protein localization and function. Acylation is essential for human immunodeficiency virus 1 (HIV-1) assembly and budding of HIV-1 from the plasma membrane in lipid raft microdomains and is mediated by myristoylation of the
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