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Merck
CN

O6877

Sigma-Aldrich

Octanoyl coenzyme A 锂盐 水合物

≥95% (HPLC)

别名:

Capryloyl coenzyme A 锂盐 水合物

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关于此项目

经验公式(希尔记法):
C29H50N7O17P3S · xLi+ · yH2O
CAS Number:
分子量:
893.73 (free acid basis)
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
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生物来源

synthetic (organic)

质量水平

方案

≥95% (HPLC)

表单

powder

溶解性

H2O: soluble-25 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

[Li+].[Li+].[Li+].O.CCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23

InChI

1S/C29H50N7O17P3S.3Li.H2O/c1-4-5-6-7-8-9-20(38)57-13-12-31-19(37)10-11-32-27(41)24(40)29(2,3)15-50-56(47,48)53-55(45,46)49-14-18-23(52-54(42,43)44)22(39)28(51-18)36-17-35-21-25(30)33-16-34-26(21)36;;;;/h16-18,22-24,28,39-40H,4-15H2,1-3H3,(H,31,37)(H,32,41)(H,45,46)(H,47,48)(H2,30,33,34)(H2,42,43,44);;;;1H2/q;3*+1;/p-3/t18-,22-,23-,24+,28-;;;;/m1..../s1

InChI key

VWXPWBSHKDXAFH-SMMZWZJBSA-K

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应用

辅酶 A 作为酰基载体,乙酰辅酶 A 发挥作用。辛酰辅酶 A 是 饥饿素O-酰基转移酶 (s)(山羊)对饥饿素和其他肽进行酰化(辛酰化)的供体分子。

生化/生理作用

与辅酶 A 共价连接的中链脂肪酸。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The expression of ghrelin O-acyltransferase (GOAT) in human tissues.
Lim CT, Kola B, Grossman A, Korbonits M.
Endocrine J., 58, 707-710 (2011)
Amparo Romero et al.
European journal of endocrinology, 163(1), 1-8 (2010-04-28)
The ghrelin-ghrelin receptor system is one of the most important mechanisms regulating energy balance and metabolism. Among other actions, central and peripheral administration of ghrelin increases food intake and adiposity. During the last years, many efforts have been made in
Jing Yang et al.
Cell, 132(3), 387-396 (2008-02-13)
Ghrelin is a 28 amino acid, appetite-stimulating peptide hormone secreted by the food-deprived stomach. Serine-3 of ghrelin is acylated with an eight-carbon fatty acid, octanoate, which is required for its endocrine actions. Here, we identify GOAT (Ghrelin O-Acyltransferase), a polytopic
Takehito Okui et al.
Arteriosclerosis, thrombosis, and vascular biology, 41(2), 755-768 (2020-12-29)
Vascular calcification is a critical pathology associated with increased cardiovascular event risk, but there are no Food and Drug Administration-approved anticalcific therapies. We hypothesized and validated that an unbiased screening approach would identify novel mediators of human vascular calcification. Approach
Hector Mendez-Figueroa et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 26(2), 150-154 (2012-08-30)
To measure the effect labor exerts on fatty acid (FA) oxidation in term human placentas, and to compare enzymes expression and activity between placenta and liver. Placental samples were collected: (a) scheduled non-labored cesarean section and (b) normal vaginal delivery

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