O9765
荭草苷
≥97% (HPLC)
别名:
8-β-D-Glucopyranosyl-3′,4′,5,7-四羟基黄酮, 荭草素, 荭草素 8-C-β-D-吡喃葡萄糖苷, 荭草苷
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关于此项目
经验公式（希尔记法）:
C21H20O11
化学文摘社编号:
分子量:
448.38
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25
质量水平
方案
≥97% (HPLC)
表单
powder
颜色
yellow
溶解性
1 M NaOH: 1 mg/mL, clear, yellow-orange
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
2-8°C
SMILES字符串
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4
InChI
1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1
InChI key
PLAPMLGJVGLZOV-VPRICQMDSA-N
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一般描述
荭草素（ORI）是一种木犀草素衍生物，也是水溶性8-C糖苷膳食黄酮。它的化学结构中有一个酮基、两个醚基和苯基。荭草素来源于多种药用植物，如O Ocimum sanctum（圣罗勒）、Phyllostachys类（竹叶）、Passiflora 类、Trollius类等。
应用
荭草素已被用于：
- 作为抗炎症和抗增殖剂用于测试其对大鼠模型中1,2-二甲基肼（DMH）引起的结肠直肠癌的保护作用
- 作为类黄酮用于研究其对抗霉素A引起的鼠C2C12骨骼肌细胞中线粒体功能障碍的保护作用
- 作为流感病毒聚合酶PA亚单位的潜在核酸内切酶抑制剂
生化/生理作用
荭草素对于过氧化氢引起的SH-SY5Y神经母细胞具有神经保护作用。 它具有抗氧化、抗炎症、抗老化、抗抑郁剂、血管舒张和心脏保护作用。
黄酮苷存在于阿萨伊树、金梅草和西番莲中。抗病毒、抗菌和抗氧化剂。具有防辐射活性。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 96, 1253-1266 (2017-12-05)
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A Rovirosa et al.
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Sinenhlanhla X H Mthembu et al.
Molecules (Basel, Switzerland), 26(20) (2021-10-24)
The current study investigated the physiological effects of flavonoids found in daily consumed rooibos tea, aspalathin, isoorientin, and orientin on improving processes involved in mitochondrial function in C2C12 myotubes. To achieve this, C2C12 myotubes were exposed to a mitochondrial channel
Benjamin Ngee Tiing Law et al.
Molecular medicine reports, 9(3), 947-954 (2013-12-25)
Neurodegenerative diseases remain a global issue which affects the ageing population. Efforts towards determining their aetiologies to understand their pathogenic mechanisms are underway in order to identify a pathway through which therapeutic measures can be applied. One such pathogenic mechanism
Detection of atrial tachyarrhythmias by transesophageal pacing and recording at rest and during exercise in children with ventricular preexcitation.
F Drago et al.
The American journal of cardiology, 69(12), 1098-1099 (1992-04-25)
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