P0022
PS48
≥98% (HPLC)
别名:
5-（4-氯苯基）-3-苯基-戊-2-烯酸
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经验公式（希尔记法）:
C17H15ClO2
化学文摘社编号:
分子量:
286.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
LLJYFDRQFPQGNY-QINSGFPZSA-N
SMILES string
OC(=O)\C=C(\CCc1ccc(Cl)cc1)c2ccccc2
InChI
1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to off-white
solubility
DMSO: >20 mg/mL
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
PDK1（磷酸肌醇依赖性蛋白激酶1）激活剂，与HM/PIF结合口袋而不是ATP结合位点结合。
PS48是一种PDK1（磷酸肌醇依赖性蛋白激酶1）激活剂，可与HM/PIF结合口袋而不是ATP结合位点结合。PS48是靶向蛋白激酶催化结构域上与ATP结合位点不相邻或不重叠的调节结合位点的少数几种真正的变构化合物之一。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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