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Merck
CN

P0130

Sigma-Aldrich

黄体酮

≥99% (HPLC), powder, maturation of the uterine endothelium inducer

别名:

4-孕烯-3,20-二酮

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关于此项目

经验公式(希尔记法):
C21H30O2
化学文摘社编号:
分子量:
314.46
Beilstein:
1915950
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

黄体酮, ≥99%

生物来源

synthetic (organic)

质量水平

无菌性

non-sterile

方案

≥99%

表单

powder

mp

128-132 °C (lit.)

溶解性

chloroform: 50 mg/mL, clear, colorless to light yellow

创始人

Abbott

运输

ambient

储存温度

room temp

SMILES字符串

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

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生化/生理作用

诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。
诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。 孕激素与乳腺癌发病有关。

特点和优势

该化合物由 Abbott开发。想要浏览其他由制药公司开发的化合物以及已批准物/候选药物清单, 请单击此处

其他说明

黄体分泌的类固醇激素。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 2 - Lact. - Repr. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

涉药品监管产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alicia T Pate et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 317(2), R328-R336 (2019-05-30)
Nesfatin-1 is a peptide derived from the nucleobindin 2 (Nucb2) precursor protein that has been shown to exert potent effects on appetite and cardiovascular function in male animals. Sex hormones modulate the expression of Nucb2 in several species, including goldfish
Nina Lisofsky et al.
NeuroImage, 118, 154-162 (2015-06-10)
Hippocampal volume has been shown to be sensitive to variations in estrogen and progesterone levels across rodents' estrous cycle. However, little is known about the covariation of hormone levels and brain structure in the course of the human menstrual cycle.
Danijela Konforte et al.
Clinical chemistry, 59(8), 1215-1227 (2013-05-03)
Pediatric endocrinopathies are commonly diagnosed and monitored by measuring hormones of the hypothalamic-pituitary-gonadal axis. Because growth and development can markedly influence normal circulating concentrations of fertility hormones, accurate reference intervals established on the basis of a healthy, nonhospitalized pediatric population
Rudolf Kaaks et al.
International journal of cancer, 134(8), 1947-1957 (2013-10-25)
Results from prospective studies on premenopausal serum hormone levels in relation to breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a case-control study nested within the prospective European Prospective Investigation into Cancer and Nutrition (EPIC)
Cathrin Brisken
Nature reviews. Cancer, 13(6), 385-396 (2013-05-25)
Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxifen, and aromatase

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