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Merck
CN

P0240

PRAK Substrate Peptide

1 mg/mL in H2O, ≥98% (HPLC), aqueous solution

别名:

P38 Regulated/Activated Protein Kinase Substrate Peptide

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关于此项目

NACRES:
NA.77
PubChem Substance ID:
329820024
UNSPSC Code:
12352202
MDL number:
MFCD02682926

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InChI

1S/C51H98N18O13/c1-26(2)23-35(65-42(74)32(16-10-12-20-53)62-40(72)31(54)15-9-11-19-52)44(76)64-33(17-13-21-59-50(55)56)41(73)63-34(18-14-22-60-51(57)58)43(75)69-39(30(8)71)48(80)66-36(24-27(3)4)45(77)67-37(25-70)46(78)68-38(28(5)6)47(79)61-29(7)49(81)82/h26-39,70-71H,9-25,52-54H2,1-8H3,(H,61,79)(H,62,72)(H,63,73)(H,64,76)(H,65,74)(H,66,80)(H,67,77)(H,68,78)(H,69,75)(H,81,82)(H4,55,56,59)(H4,57,58,60)/t29-,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-/m0/s1

SMILES string

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(O)=O

InChI key

QDSZECPRZNYZJS-DVHCFKBKSA-N

assay

≥98% (HPLC)

form

aqueous solution

mol wt

1171 by amino acid sequence

concentration

1 mg/mL in H2O

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Biochem/physiol Actions

Peptide substrate for the enzyme PRAK (P38 regulated/activated protein kinase)

Features and Benefits

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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分析证书(COA)

Lot/Batch Number
071K1456

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L New et al.
The EMBO journal, 17(12), 3372-3384 (1998-06-17)
We have identified and cloned a novel serine/ threonine kinase, p38-regulated/activated protein kinase (PRAK). PRAK is a 471 amino acid protein with 20-30% sequence identity to the known MAP kinase-regulated protein kinases RSK1/2/3, MNK1/2 and MAPKAP-K2/3. PRAK was found to

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