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Merck
CN

P0376

苯酚 β-D-葡萄糖醛酸 钠盐

β-glucuronidase substrate, chromogenic, ≥90% (TLC), powder

别名:

酚酞单-β-葡糖苷酸, 酚酞葡糖醛酸

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关于此项目

线性分子式:
C26H21O10Na
化学文摘社编号:
6820-54-8
分子量:
516.43
NACRES:
NA.28
PubChem Substance ID:
329820033
UNSPSC Code:
12352204
EC Number:
229-896-3
MDL number:
MFCD00051200

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产品名称

苯酚 β-D-葡萄糖醛酸 钠盐, β-glucuronidase substrate

InChI

1S/C26H22O10.Na/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32;/h1-12,19-22,25,27-30H,(H,31,32);/q;+1/p-1/t19-,20-,21+,22-,25+,26?;/m0./s1

InChI key

GBLJULUMBNYFAK-PDFLYTMFSA-M

SMILES string

[Na+].O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C([O-])=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5

assay

≥90% (TLC)

form

powder

solubility

H2O: soluble 5 mg/mL

storage temp.

−20°C

Quality Level

200

Biochem/physiol Actions

酚酞β-D-葡萄糖醛酸钠盐是一种β葡萄糖醛酸酶。它由注射酚酞的兔的尿生物合成。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000512710
0000512707
0000512706
0000512708
0000512708

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Chromogenic substrates II. Phenolphthalein glucuronic acid as substrate for the assay of glucuronidase activity
Talalay P, et al.
The Journal of Biological Chemistry, 166(2), 757-772 (1946)
[9] Preparation and assay of substrates for $\beta$-glucuronidase
Fishman WH
Test (1957)
Improvement in intestinal function and health by the peel fiber derived from Citrus sinensis L cv Liucheng
Chi-Fai Chau, Fuu Sheu, Ya-Ling Huang and Li-Hung Su
Journal of the Science of Food and Agriculture, 85, 1211-1216 (2005)
L K Griffeth et al.
Drug metabolism and disposition: the biological fate of chemicals, 13(4), 391-397 (1985-07-01)
A previously validated small mammal trauma model, hind-limb ischemia secondary to infrarenal aortic ligation in the rat, was utilized to investigate the effects of traumatic injury on hepatic glucuronidation activity. As was previously observed with hepatic oxidative drug metabolism, model
Z K Sharaiha et al.
Digestive diseases and sciences, 28(9), 827-832 (1983-09-01)
Phenolphthalein is an odorless, tasteless compound, poorly soluble in water, but readily soluble in alcohol or ether. Although its laxative activity was discovered in 1902, the mechanism of action remains unclear. Phenolphthalein has been found to be an ineffective laxative
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