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Merck
CN

P0376

Sigma-Aldrich

苯酚 β-D-葡萄糖醛酸 钠盐

β-glucuronidase substrate, chromogenic, ≥90% (TLC), powder

别名:

酚酞单-β-葡糖苷酸, 酚酞葡糖醛酸

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关于此项目

线性分子式:
C26H21O10Na
化学文摘社编号:
6820-54-8
分子量:
516.43
EC 号:
229-896-3
MDL编号:
MFCD00051200
UNSPSC代码:
12352204
PubChem化学物质编号:
329820033
NACRES:
NA.28

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产品名称

苯酚 β-D-葡萄糖醛酸 钠盐, β-glucuronidase substrate

方案

≥90% (TLC)

表单

powder

溶解性

H2O: soluble 5 mg/mL

储存温度

−20°C

SMILES字符串

[Na+].O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C([O-])=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5

InChI

1S/C26H22O10.Na/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32;/h1-12,19-22,25,27-30H,(H,31,32);/q;+1/p-1/t19-,20-,21+,22-,25+,26?;/m0./s1

InChI key

GBLJULUMBNYFAK-PDFLYTMFSA-M

生化/生理作用

酚酞β-D-葡萄糖醛酸钠盐是一种β葡萄糖醛酸酶。它由注射酚酞的兔的尿生物合成。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000431955
0000431955
0000406712
0000397224
0000389003

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[9] Preparation and assay of substrates for $\beta$-glucuronidase
Fishman WH
Test (1957)
Chromogenic substrates II. Phenolphthalein glucuronic acid as substrate for the assay of glucuronidase activity
Talalay P, et al.
The Journal of Biological Chemistry, 166(2), 757-772 (1946)
Improvement in intestinal function and health by the peel fiber derived from Citrus sinensis L cv Liucheng
Chi-Fai Chau, Fuu Sheu, Ya-Ling Huang and Li-Hung Su
Journal of the Science of Food and Agriculture, 85, 1211-1216 (2005)
B S Anand et al.
Alimentary pharmacology & therapeutics, 8(5), 559-562 (1994-10-01)
Phenolphthalein is widely used as a safe and effective laxative. After oral administration, phenolphthalein is absorbed in the small bowel and is conjugated in the liver to phenolphthalein glucuronide which passes into the colon where it is deconjugated and the
Tatsuyuki Marumo et al.
Journal of gastroenterology, 39(10), 981-987 (2004-11-19)
Hepatocytes in zone 1 of the hepatic lobule play a role in the uptake and biliary excretion of bile acids and organic anions under physiological conditions, and hepatocytes in zone 3 may play a role only when there is a
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