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Merck
CN

P0501

酚酞β-D-葡萄糖苷酸

β-glucuronidase substrate

别名:

酚酞β-D-葡萄糖醛酸, 酚酞单-β-D-葡糖醛酸, 酚酞葡糖醛酸

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关于此项目

经验公式（希尔记法）:
C26H22O10
化学文摘社编号:
15265-26-6
分子量:
494.45
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
24898108
MDL number:
MFCD00135881
Beilstein/REAXYS Number:
68526

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产品名称

酚酞β-D-葡萄糖苷酸, β-glucuronidase substrate

InChI

1S/C26H22O10/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32/h1-12,19-22,25,27-30H,(H,31,32)/t19-,20-,21+,22-,25+,26?/m0/s1

SMILES string

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5

InChI key

FXJYOZKDDSONLX-XADSOVDISA-N

assay

≥97% (TLC)

form

powder

solubility

H2O: soluble 100 mg/mL

storage temp.

−20°C

Quality Level

200

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Application

β-葡萄糖醛酸苷酶活性由0.01m酚酞β-D-葡萄糖苷酸释放的酚酞量测定。
酚酞β-D-葡糖苷酸已用作粪便细菌中β-D-葡萄糖醛酸酶活性检测的底物。

Biochem/physiol Actions

酚酞β-D-葡糖苷酸是β-葡萄糖醛酸酶的发色底物，可在552 nm波长下测定反应获得的有色产物。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000509573
0000509573
0000509571
0000509571
0000493716

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Ball Al, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 23(1), 131-135 (2008)
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Water science and technology : a journal of the International Association on Water Pollution Research, 83(6), 1399-1406 (2021-03-27)
Monitoring of Escherichia coli concentrations in river water (RW) is essential to identify fecal pollution of the river. The objective of this study was to assess the suitability of a novel, simple and high throughput method developed in our laboratory
Effects of two pomace insoluble fibres on the activities of faecal bacterial enzymes and intestinal health
Chau CF and Chen CH
European Food Research and Technology, 222(5-6), 681-685 (2006)
Intestinal health benefits of the water-soluble carbohydrate concentrate of wild grape (Vitis thunbergii) in hamsters
Huang YL, et al.
Journal of Agricultural and Food Chemistry, 60(19), 4854-4858 (2012)
Improvement in intestinal function and health by the peel fiber derived from Citrus sinensis L cv Liucheng
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Journal of the Science of Food and Agriculture, 85, 1211-1216 (2005)
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商品

Drug Conjugate Analysis using β-Glucuronidases

Drug conjugate analysis and the enzymatic hydrolysis of glucuronides

Probiotics and Human Health

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

实验方案

Enzymatic Assay of β-Glucuronidase (EC 3.2.1.31) from E. coli

Objective: To standardize a procedure for the enzymatic assay of β-Glucuronidase.

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