质量水平
方案
≥98% (TLC)
表单
powder
颜色
white to off-white
mp
167-171 °C (lit.)
溶解性
0.1 M NaOH: 0.2 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL
0.1 M HCl: 20 mg/mL
acetic acid: 50 mg/mL
H2O: insoluble
创始人
Novartis
储存温度
2-8°C
SMILES字符串
CC(C)NCC(O)COc1cccc2[nH]ccc12
InChI
1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3
InChI key
JZQKKSLKJUAGIC-UHFFFAOYSA-N
基因信息
human ... ADRB1(153), ADRB2(154), HTR1A(3350)
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应用
Pindolol has been used in intestinal transport and metabolism assays and cassette mix preparation.
生化/生理作用
β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator. Pindolol is a non-cardioselective beta-adrenergic blocking agent. It possesses intrinsic sympathomimetic activity.
β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator.
特点和优势
Shelf-life of the powder is at least five years.
This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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