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P0778

Pindolol

≥98% (TLC), β1-adrenoceptor antagonist, powder

别名:

1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol, 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol

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关于此项目

经验公式（希尔记法）:
C14H20N2O2
化学文摘社编号:
13523-86-9
分子量:
248.32
NACRES:
NA.77
PubChem Substance ID:
24277795
UNSPSC Code:
12352200
EC Number:
236-867-9
MDL number:
MFCD00010530
Assay:
≥98% (TLC)
Form:
powder
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产品名称

Pindolol, ≥98% (TLC), powder

Quality Segment

assay

≥98% (TLC)

form

powder

color

white to off-white

mp

167-171 °C (lit.)

solubility

0.1 M NaOH: 0.2 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL, 0.1 M HCl: 20 mg/mL, acetic acid: 50 mg/mL, H2O: insoluble

originator

Novartis

storage temp.

2-8°C

SMILES string

CC(C)NCC(O)COc1cccc2[nH]ccc12

InChI

1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3

InChI key

JZQKKSLKJUAGIC-UHFFFAOYSA-N

Gene Information

Application

Pindolol has been used in intestinal transport and metabolism assays and cassette mix preparation.

Biochem/physiol Actions

β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator. Pindolol is a non-cardioselective beta-adrenergic blocking agent. It possesses intrinsic sympathomimetic activity.
β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator.

Features and Benefits

Shelf-life of the powder is at least five years.
This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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象形图

Exclamation mark
GHS07

警示词

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

存储类别

11 - Combustible Solids

怎么回事？

WGK 3

PPE（个人防护设备）

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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