P0928
7-羟基吩噁嗪酮二戊醚
≥98% (TLC), Fluorimetric Cytochrome P450 substrate, powder
别名:
7-(戊氧基)-3H-吩噁嗪-3-酮
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关于此项目
经验公式（希尔记法）:
C17H17NO3
化学文摘社编号:
分子量:
283.32
Beilstein:
8394939
MDL编号:
UNSPSC代码:
12161501
PubChem化学物质编号:
NACRES:
NA.47
产品名称
7-羟基吩噁嗪酮二戊醚,
方案
≥98% (TLC)
质量水平
表单
powder
溶解性
acetonitrile: 0.95- 1.05 mg/mL, clear, orange
储存温度
2-8°C
SMILES字符串
CCCCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1
InChI
1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3
InChI key
ZPSOKQFFOYYPKC-UHFFFAOYSA-N
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相关类别
一般描述
Resorufin pentyl ether is an analog of resazurin. Resorufin is a redox probe which is colorless and non-fluorescent in its reduced state. On oxidation, it fluoresces red. Resorufin is used widely as an indicator in microbiological media. It can be used to differentiate between actively metabolizing cells and inactive or dead cells.
应用
Resorufin pentyl ether has been used as a substrate to study the effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.
生化/生理作用
Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Advances in Microbial Ecology null
E S Tzanakakis et al.
Cell motility and the cytoskeleton, 48(3), 175-189 (2001-02-27)
Cultured rat hepatocytes self-assemble into three-dimensional structures or spheroids that exhibit ultrastructural characteristics of native hepatic tissue and enhanced liver-specific functions. The spheroid formation process involves cell translocation and changes in cell shape, indicative of the reorganization of the cytoskeletal
A Pietersma et al.
Free radical research, 28(2), 137-150 (1998-06-30)
The present study was undertaken to investigate the hypothesis that multiple oxygen radical generating systems contribute to the tumor necrosis factor (TNF) alpha-stimulated transcriptional activation of the vascular cell adhesion molecule (VCAM)-1 in endothelial cells. Experimental evidence has implicated the
V Burkina et al.
Ecotoxicology and environmental safety, 79, 148-152 (2012-01-17)
Little is known about the effects of the cardiovascular drug verapamil (VRP) on metabolic processes in fish. Most calcium channel blockers including VRP are metabolized by cytochrome P450 (CYP450) enzymes. In this study we investigated the in vivo effect of
Microbial Biofilms null
商品
一期生物转化反应在药物上引入或暴露官能团，目的是增加化合物的极性。尽管一期药物代谢发生在大多数组织中，但代谢的主要和首过部位发生在肝循环期间。
Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.
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