P0981
Anti-Potassium Channel TASK-1 antibody produced in rabbit
affinity isolated antibody, lyophilized powder
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot (chemiluminescent)
Species reactivity:
human, rat
Citations:
3
Technique(s):
western blot (chemiluminescent): 1:200
Uniprot accession no.:
产品名称
Anti-Potassium Channel TASK-1 antibody produced in rabbit, affinity isolated antibody, lyophilized powder
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, rat
technique(s)
western blot (chemiluminescent): 1:200
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... KCNK3(3777)
mouse ... Kcnk3(16527)
rat ... Kcnk3(29553)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
synthetic peptide corresponding to amino acid residues 252-269 of human TASK-1 (with additional C-terminal cysteine). The epitope is highly conserved in mouse and rat TASK-1.
Physical form
Lyophilized at ~0.6 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.
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存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
Constanze Schmidt et al.
Circulation, 132(2), 82-92 (2015-05-09)
Antiarrhythmic management of atrial fibrillation (AF) remains a major clinical challenge. Mechanism-based approaches to AF therapy are sought to increase effectiveness and to provide individualized patient care. K(2P)3.1 (TASK-1 [tandem of P domains in a weak inward-rectifying K+ channel-related acid-sensitive
Alexandra Mant et al.
Channels (Austin, Tex.), 7(4), 288-302 (2013-06-29)
Acid-sensitive, two-pore domain potassium channels, K(2P)3.1 and K(2P)9.1, are implicated in cardiac and nervous tissue responses to hormones, neurotransmitters and drugs. K(2P)3.1 and K(2P)9.1 leak potassium from the cell at rest and directly impact membrane potential. Hence altering channel number
Victoria García-Morales et al.
Nature communications, 10(1), 3784-3784 (2019-08-24)
Disruption in membrane excitability contributes to malfunction and differential vulnerability of specific neuronal subpopulations in a number of neurological diseases. The adaptor protein p11, and background potassium channel TASK1, have overlapping distributions in the CNS. Here, we report that the
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