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Merck
CN

P1253

Sigma-Aldrich

卵黄高磷蛋白 来源于鸡蛋黄

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MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.81
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生物来源

egg yolk

表单

powder

储存温度

−20°C

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一般描述

蛋黄中的卵黄高磷蛋白是富含聚阴离子磷酸丝氨酸的蛋白质。该磷酸糖蛋白包含α-螺旋和β-折叠结构元件,由于磷酸丝氨酸的存在,它们的组织不良。它代表约11%的卵黄蛋白,并且是亲水性的。

应用

蛋黄中的卵黄高磷蛋白已用于:
  • 作为对照蛋白固定在芯片上用于深紫色蛋白染色,用于监测翻译后修饰
  • 作为体外酪蛋白激酶测定中酪蛋白激酶Iε的底物
  • 作为凝胶过滤色谱(GFC)和十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)中的标准品,用于定量测定蛋黄提取物中的卵黄高磷蛋白
  • 用于逐层(LbL)固定化,用于傅里叶变换红外光谱衰减全反射(FTIR-ATR)研究

生化/生理作用

蛋黄中的卵黄高磷蛋白是一种钙螯合剂,可与蛋黄中存在的铁结合。金属结合功能被用于矿物结合生物活性肽的生产中。它是一种营养保健品,具有磷酸肽生产的潜力。
通过在食物中添加蛋黄喂养大鼠的卵黄高磷蛋白导致镁、铁和钙的吸收减少,但磷的吸收没有减少。

其他说明

含8-10%磷的磷蛋白。 摩尔N/P比约为2.7。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

动植物来源生物产品
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历史批次信息供参考:

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Lot/Batch Number

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Shicui Zhang et al.
Developmental and comparative immunology, 39(1-2), 72-78 (2012-03-06)
Both innate and adaptive immune-relevant factors are transferred from mother to offspring in fishes. These maternally-transferred factors include IgM, lysozymes, lectin, cathelicidin and complement components. Recently, yolk proteins, phosvitin and lipovitellin, have been shown to be maternally-transferred factors, functioning in
P L Lowrey et al.
Science (New York, N.Y.), 288(5465), 483-492 (2000-04-25)
The tau mutation is a semidominant autosomal allele that dramatically shortens period length of circadian rhythms in Syrian hamsters. We report the molecular identification of the tau locus using genetically directed representational difference analysis to define a region of conserved
Bo Lei et al.
Journal of chromatography. A, 1223, 41-46 (2011-12-27)
The objective of this study was to develop a simple method of phosvitin purification from hen egg yolk without using organic solvents. Egg yolk was diluted with equal volume of water and stirred for one hour at room temperature, followed
Kodai Yamane et al.
Fish physiology and biochemistry, 39(2), 373-390 (2012-08-25)
Elasmobranchs (sharks and rays) exhibit unique reproductive characteristics and, in contrast to the situation in teleosts, very little is known about the identity, structure and physical characteristics of their egg yolk proteins. The aims of this study were to (1)
Denise Young et al.
Journal of agricultural and food chemistry, 59(17), 9207-9218 (2011-08-02)
Oxidative stress is involved in the initiation and propagation of chronic intestinal pathologies. Bioactive peptides such as egg yolk-derived phosvitin phosphopeptides (PPP3) have been previously shown to reduce in vitro oxidative stress by up-regulating glutathione synthesis and antioxidant enzyme activities.

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