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Merck
CN

P1411

多粘菌素 B-琼脂糖

aqueous glycerol suspension

别名:

PMB

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UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
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biological source

synthetic (organic)

form

aqueous glycerol suspension

extent of labeling

~1 mg per mL

technique(s)

affinity chromatography: suitable

matrix

Cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

200-500 μg/mL binding capacity (lipopolysaccharide)(from Escherichia coli serotype 0128:B12)

suitability

suitable for chromatography

storage temp.

2-8°C

Quality Level

Application

可用于从溶液中去除内毒素
多粘菌素 B-琼脂糖用于蛋白质色谱、亲和色谱和专业树脂。多粘菌素 B-琼脂糖已用于研究牙周炎和牙髓感染,以及肥胖和 2 型糖尿病。

Physical form

悬浮于含有 0.02% 叠氮化钠的 50% 甘油中

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A C Issekutz
Journal of immunological methods, 61(3), 275-281 (1983-07-29)
Endotoxins liberated by gram-negative bacteria are frequent contaminants of aqueous and physiological solutions. Because of their potent biological effects in vivo and in vitro, it is often necessary to eliminate even minute quantities of endotoxin from such solutions. A process
Martín López et al.
Journal of immunology (Baltimore, Md. : 1950), 170(5), 2409-2416 (2003-02-21)
Macrophages infected with Mycobacterium tuberculosis undergo increased rates of apoptosis. Important objectives are to define the microbial factors that cause apoptosis, the mechanisms involved and the impact on infection. The 19-kDa M. tuberculosis glycolipoprotein (p19) is both cell wall-associated and
K W Talmadge et al.
Journal of chromatography, 476, 175-185 (1989-08-04)
A new affinity column packing for removal of endotoxins has been prepared by coupling USP drug-quality polymyxin B to Affi-Prep, a novel synthetic macroporous polymer. Affi-Prep Polymyxin binds endotoxins from a number of different strains of gram-negative bacteria. Endotoxin binding
Dina B AbuSamra et al.
Cells, 10(2) (2021-02-13)
Chemokines are an extended group of chemoattractant cytokines responsible for the recruitment of leukocytes into tissues. Among them, interferon-γ-inducible protein 10 (CXCL10) is abundantly expressed following inflammatory stimuli and participates in the trafficking of monocytes and activated T cells into
K Stuhlmeier et al.
Clinical and experimental immunology, 84(2), 317-323 (1991-05-01)
Coumarin as well as its derivatives 7-OH coumarin and 4-OH coumarin were found to stimulate interleukin-1 beta (IL-1 beta) release from freshly isolated human mononuclear cells (MNC) if the culture medium contained fetal calf serum. Under serum-free conditions, almost no

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