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Merck
CN

P1751

D -苯丙氨酸

≥98% (HPLC)

别名:

(R)-2-氨基-3-苯丙酸

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关于此项目

经验公式(希尔记法):
C9H11NO2
化学文摘社编号:
分子量:
165.19
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-603-5
MDL number:
Beilstein/REAXYS Number:
2804068
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产品名称

D -苯丙氨酸, ≥98% (HPLC)

InChI key

COLNVLDHVKWLRT-MRVPVSSYSA-N

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1

SMILES string

N[C@H](Cc1ccccc1)C(O)=O

assay

≥98% (HPLC)

form

powder

color

white to off-white

mp

273-276 °C

application(s)

cell analysis

Quality Level

Gene Information

Application

<ul>
<li><strong>论文标题: </strong> Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma.D-苯丙氨酸用于提高<em>体内</em>肽稳定性(Chen P et al., 2023)。</li>
<li><strong>论文标题: </strong> Mechanistic aspects of the transamination reactions catalyzed by D-amino acid transaminase from Haliscomenobacter hydrossis.研究特定的细菌转氨过程,D-苯丙氨酸为酶底物。适用生物催化和合成生物学(Bakunova AK et al., 2023)。</li>
</ul>

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jincheng Ni et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(2) (2020-12-30)
Spin angular momentum of light is vital to investigate enantiomers characterized by circular dichroism (CD), widely adopted in biology, chemistry, and material science. However, to discriminate chiral materials with multiscale features, CD spectroscopy normally requires wavelength-swept laser sources as well
Andrew T Schuster et al.
Gastroenterology, 148(7), 1405-1416 (2015-02-24)
Defects in colonic epithelial barrier defenses are associated with ulcerative colitis (UC). The proteins that regulate bacterial clearance in the colonic epithelium have not been completely identified. The Drosophila chromosome-associated protein D3 (dCAP-D3) regulates responses to bacterial infection. We examined
Suneela S Dhaneshwar et al.
European journal of medicinal chemistry, 44(1), 131-142 (2008-05-13)
Mutual amide prodrugs of 4-aminosalicylic acid with D-phenylalanine and L-tryptophan were synthesized for targeted drug delivery to the inflamed gut tissue in inflammatory bowel disease. Stability studies in aqueous buffers (pH 1.2 and 7.4) showed that the synthesized prodrugs were
Ruth Milkereit et al.
Nature communications, 6, 7250-7250 (2015-05-23)
Mammalian target of rapamycin 1 (mTORC1), a master regulator of cellular growth, is activated downstream of growth factors, energy signalling and intracellular essential amino acids (EAAs) such as Leu. mTORC1 activation occurs at the lysosomal membrane, and involves V-ATPase stimulation
Florian Beaumatin et al.
Molecular cell, 76(1), 163-176 (2019-09-08)
Sensing nutrient availability is essential for appropriate cellular growth, and mTORC1 is a major regulator of this process. Mechanisms causing mTORC1 activation are, however, complex and diverse. We report here an additional important step in the activation of mTORC1, which

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