P1937
磷酸肌酸 二(三羟甲基氨基甲烷) 盐
≥97% (enzymatic)
别名:
N-(亚氨基[膦氨基]甲基)-N-甲基甘氨酸, 磷酸肌酸二（三）盐
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关于此项目
经验公式（希尔记法）:
C4H10N3O5P · 2C4H11NO3
化学文摘社编号:
分子量:
453.38
PubChem Substance ID:
NACRES:
NA.77
MDL number:
UNSPSC Code:
12352204
产品名称
磷酸肌酸 二(三羟甲基氨基甲烷) 盐, ≥97% (enzymatic)
SMILES string
NC(CO)(CO)CO.NC(CO)(CO)CO.CN(CC(O)=O)C(=N)NP(O)(O)=O
InChI
1S/C4H10N3O5P.2C4H11NO3/c1-7(2-3(8)9)4(5)6-13(10,11)12;2*5-4(1-6,2-7)3-8/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);2*6-8H,1-3,5H2
InChI key
UPPBKCOGWJTQMJ-UHFFFAOYSA-N
biological source
rabbit muscle
assay
≥97% (enzymatic)
form
powder
color
white
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless
cation traces
Na: ≤0.1%
storage temp.
−20°C
Quality Level
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Application
用于不需要碱金属离子的系统。
Biochem/physiol Actions
脊椎动物和一些无脊椎动物肌肉中的高能磷酸盐库；为 ADP-ATP 转化提供磷酸盐。作为高能磷酸盐的非氧化储存库，磷酸肌酸对脑神经元的缺氧和缺血性损伤具有保护作用。
脊椎动物和一些无脊椎动物肌肉中的高能磷酸贮存器；为 ADP-ATP 转化提供磷酸。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Sofía Muñoz et al.
Molecular cell, 74(4), 664-673 (2019-03-30)
Cohesin is a conserved, ring-shaped protein complex that topologically embraces DNA. Its central role in genome organization includes functions in sister chromatid cohesion, DNA repair, and transcriptional regulation. Cohesin loading onto chromosomes requires the Scc2-Scc4 cohesin loader, whose presence on
Lou Beaulieu-Laroche et al.
Neuron, 103(2), 235-241 (2019-06-11)
Dendritic integration can expand the information-processing capabilities of neurons. However, the recruitment of active dendritic processing in vivo and its relationship to somatic activity remain poorly understood. Here, we use two-photon GCaMP6f imaging to simultaneously monitor dendritic and somatic compartments in
Guixin Zhu et al.
Cell reports, 33(9), 108418-108418 (2020-12-03)
Neurodegenerative diseases are characterized by the formation and propagation of protein aggregates, especially amyloid fibrils. However, what normally suppresses protein misfolding and aggregation in metazoan cells remains incompletely understood. Here, we show that TRIM11, a member of the metazoan tripartite
Alexandra Colin et al.
Current biology : CB, 28(16), 2647-2656 (2018-08-14)
Coordination between actin filaments and microtubules is critical to complete important steps during cell division. For instance, cytoplasmic actin filament dynamics play an active role in the off-center positioning of the spindle during metaphase I in mouse oocytes [1-3] or
Trace Thome et al.
American journal of physiology. Cell physiology, 317(4), C701-C713 (2019-07-11)
Chronic kidney disease (CKD) leads to increased skeletal muscle fatigue, weakness, and atrophy. Previous work has implicated mitochondria within the skeletal muscle as a mediator of muscle dysfunction in CKD; however, the mechanisms underlying mitochondrial dysfunction in CKD are not
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