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Merck
CN

P2178

Sigma-Aldrich

Pro-Asp-Val-Asp-His-Val-Phe-Leu-Arg-Phe-NH2

≥97% (HPLC)

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关于此项目

经验公式(希尔记法):
C59H86N16O14
化学文摘社编号:
分子量:
1243.41
MDL编号:
UNSPSC代码:
12352200
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方案

≥97% (HPLC)

储存温度

−20°C

SMILES字符串

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CCCN3)C(C)C)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc4ccccc4)C(N)=O

生化/生理作用

Cardioinhibitory; inhibits contraction of the oviduct visceral muscle, but potentiates contraction of the extensortibiae muscle

其他说明

FMRF-amide-like neuropeptide originally isolated from locust (Schistocera gregaria)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Z Wang et al.
Peptides, 16(7), 1181-1186 (1995-01-01)
In the oviduct of Locusta migratoria, an inhibitory neuropeptide, PDVDHVFLRFamide (SchistoFLRFamide) has separate binding and activation regions. VFLRFamide is the minimum sequence required for binding, which is comparable to the parent peptide, whereas the His residue, which does not contribute
Rodney Kwok et al.
Peptides, 23(11), 1925-1932 (2002-11-15)
We have developed a semi-intact preparation-consisting of an isolated oviduct with abdominal ganglia VII and VIII intact and attached-with which to characterize the effects on oviduct contraction, of peptides that are bath applied to CNS tissues. The work presented here
S Robb et al.
Biochemical and biophysical research communications, 160(2), 850-856 (1989-04-28)
We have isolated a neuropeptide, related to the Phe-Met-Arg-Phe-NH2 family, from the thoracic nervous system of the locust, Schistocerca gregaria, using a purification system based on the radioimmunoassay of high pressure liquid chromatography fractions. The primary sequence of this locust
A B Lange et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(20), 9250-9253 (1995-09-26)
We describe a nonpeptide mimetic analog of an invertebrate peptide receptor. Benzethonium chloride (Bztc) is an agonist of the SchistoFLRFamide (PDVDHVFLRFamide) receptors found on locust oviducts. Bztc competitively displaces [125I-labeled Y1]SchistoFLRFamide binding to both high- and low-affinity receptors of membrane
L Schoofs et al.
Peptides, 14(3), 409-421 (1993-05-01)
An amidated decapeptide, exhibiting strong inhibitory activity of spontaneous visceral muscle movements, was isolated from 9000 brain-corpora cardiaca-corpora allata-subesophageal ganglion complexes of the migratory locust, Locusta migratoria. During the process of HPLC purifications, the biological activity of the fractions was

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