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Merck
CN

P2178

Pro-Asp-Val-Asp-His-Val-Phe-Leu-Arg-Phe-NH2

≥97% (HPLC)

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关于此项目

经验公式(希尔记法):
C59H86N16O14
化学文摘社编号:
分子量:
1243.41
UNSPSC Code:
12352200
MDL number:
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assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CCCN3)C(C)C)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc4ccccc4)C(N)=O

Biochem/physiol Actions

Cardioinhibitory; inhibits contraction of the oviduct visceral muscle, but potentiates contraction of the extensortibiae muscle

Other Notes

FMRF-amide-like neuropeptide originally isolated from locust (Schistocera gregaria)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sharon R Hill et al.
Journal of insect physiology, 51(1), 1-9 (2005-02-03)
We have investigated the effect of the locust myosuppressin, SchistoFLRFamide, on the activity of amylase and alpha-glucosidase in the midgut of 2-week old male locusts. Total enzyme activity in the lumen contents and tissue extracts of midguts responds to SchistoFLRFamide
Z Wang et al.
Neuropeptides, 28(5), 261-266 (1995-05-01)
In the oviduct of Locusta migratoria, a FMRFamide-related peptide, PDVDHVFLRFamide (SchistoFLRFamide) acts as a neuromodulator, inhibiting spontaneous and induced muscle contraction. In this study, we have used N-terminal truncated peptides to show that PDVDHVFLRFamide has separated binding and activation regions.
Z Wang et al.
Neuropeptides, 28(3), 147-155 (1995-03-01)
The possible mode of action of an inhibitory neuropeptide SchistoFLRFamide (PDVDHVFLRFamide) on locust oviduct visceral muscle was studied by examining its ability to inhibit calcium ionophore A23187-, caffeine- or phorbol ester-induced oviduct contractions. A23187-induced muscle contractions included two components: one
L S Swales et al.
Cell and tissue research, 281(2), 339-348 (1995-08-01)
SchistoFLRFamide (PDVDHVFLRF-NH2) is one of the major endogenous neuropeptides of the FMRFamide family found in the nervous system of the locust, Schistocerca gregaria. To gain insights into the potential physiological roles of this neuropeptide we have examined the distribution of
J Clark et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 189(2), 105-114 (2003-02-28)
Octopamine was identified in the spermathecal tissue of Locusta migratoria using HPLC and immunohistochemical techniques. Octopamine-like immunoreactive unpaired median neurons were identified in the VIIth and VIIIth (terminal) abdominal ganglia and octopamine-like immunoreactive axons were present in the ventral ovipositor

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