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Merck
CN

P2191

聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide (50:50), mol wt 30,000-60,000

别名:

LACTEL® B6010-2, PLGA

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25
MDL number:
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feed ratio

lactide:glycolide (50:50)

Quality Level

mol wt

30,000-60,000

storage temp.

−20°C

SMILES string

OCC(O)=O.CC(O)C(O)=O

InChI key

XBBVURRQGJPTHH-UHFFFAOYSA-N

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General description

聚(D,L-丙交酯-共-乙交酯)是一种可生物降解的生物相容性聚合物,可用于药物输送。它可用于治疗类风湿性关节炎、溃疡性结肠炎、克罗恩病、炎性肺病、以及眼部炎性疾病。聚(D,L-丙交酯-共-乙交酯)可作为潜在的癌症治疗靶标起作用。

Application

聚(D,L-丙交酯-共-乙交酯)已经用于在凝胶中提高和维持乳酸盐单体水平,其浓度与皮肤伤口有关。

Features and Benefits

控释生物活性剂、缝线和可生物吸收植入器件。

Physical form

具有生物相容性且可生物降解的聚合物。

Legal Information

Lactel is a registered trademark of Evonik Corp

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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PLGA-based nanoparticles: an overview of biomedical applications
Danhier F, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 161(2), 505-522 (2012)
Characterization of biodegradable poly (D, L-lactide-co-glycolide) polymers and microspheres
Hausberger AG and DeLuca PP
Journal of Pharmaceutical and Biomedical Analysis, 13(6), 747-760 (1995)
Habibun Nabi et al.
Parasitology research, 116(1), 359-370 (2016-10-28)
Toxoplasmosis is one of the most common zoonotic protozoal diseases. Recent advances in biotechnology have produced recombinant protein, which are immunogenic, and progress in nano-pharmaceutics has generated encapsulated protein in nanospheres, which are suitable for vaccine delivery. DNA was extracted
Ahmed A Abd-Rabou et al.
Biological trace element research, 193(2), 377-389 (2019-05-09)
Colon cancer in men and breast cancer in women are regarded as major health burdens, accounting for majority of cancer diagnoses globally. Doxorubicin (DOX) resistance in breast and colon cancers represents the main reason of unsuccessful therapy. The rationale of
Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms
Hunt TK, et al.
Antioxidants & Redox Signaling, 9(8), 1115-1124 (2007)

全球贸易项目编号

货号GTIN
P2191-1G04061835513932
P2191-5G04061835513949

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