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Merck
CN

P222

Pandinotoxin-Kα

>99%, powder

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关于此项目

经验公式(希尔记法):
C169H267N53O48S7
化学文摘社编号:
分子量:
4033.71
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
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assay

>99%

form

powder

color

off-white

storage temp.

−20°C

General description

Pandinotoxin (PiTX)-Kα is a 35 amino acid peptide isolated from venom of the scorpion Pandinus imperaton. PiTX-Kβ and PiTXγ are other two members of pandinotoxin group. All the three pandinotoxins have structures similar to another scorpion toxin charybdotoxin (ChTX). The structure of PiTXs contains a β-sheet at the C- terminal end with three cysteines which is linked to the central α-helix by two disulfide bridges (C17-C35 and C13-C33) and to an extended amino-terminal fragment by the third disulfide bridge (C7-C28).

Biochem/physiol Actions

Pandinotoxin (PiTX) –Kα along with PiTX-Kβ and PiTXγ plays a vital role in blocking voltage-gated K+ channels.

Legal Information

Sold with the permission of University of Maryland.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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