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Merck
CN

P2517

L-α-磷脂酰肌醇 铵盐 溶液 来源于牛肝脏

10 mg/mL in chloroform, ≥98% (TLC)

别名:

1,2-二酰基-sn-甘油-3-磷酸基-(1-D-myo-肌醇), PI, PtdIns

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关于此项目

NACRES:
NA.77
UNSPSC Code:
12352200
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产品名称

L-α-磷脂酰肌醇 铵盐 溶液 来源于牛肝脏, 10 mg/mL in chloroform, ≥98% (TLC)

assay

≥98% (TLC)

concentration

10 mg/mL in chloroform

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

磷脂膜组分,磷酸肌醇的前体。
Phosphatidylinositol is a phosphoglyceride, containing inositol as a cyclohexanol head group. The phosphatidylinositol signaling pathway is also called as double signaling pathway as it generates two secondary messengers. It is associated with a number of physiological processes in plants. This includes the development of pollen and vascular organs, root and root hair growth, hormone response and stress tolerance.

Other Notes

主要含硬脂酸和花生四烯酸。

Features and Benefits

This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
易制毒化学品(2类)
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Functional Characterization of Arabidopsis Phosphatidylinositol Monophosphate 5-kinase 2 in Lateral Root Development, Gravitropism and Salt Tolerance, 2-2 (2014)
Sarah J Tilley et al.
Structure (London, England : 1993), 12(2), 317-326 (2004-02-14)
Phosphatidylinositol transfer protein alpha (PITPalpha) selectively transports and promotes exchange of phosphatidylinositol (PI) and phosphatidylcholine (PC) between lipid bilayers. In higher eukaryotes PITPalpha is required for cellular functions such as phospholipase C-mediated signaling, regulated exocytosis, and secretory vesicle formation. We
S J Heydrick et al.
The Journal of clinical investigation, 91(4), 1358-1366 (1993-04-01)
Activation of phosphatidylinositol-3-kinase (PI3K) is one of the earliest postreceptor events in the insulin signaling pathway. Incubation of soleus muscles from lean mice with 50 nM insulin caused a 3-10-fold increase in antiphosphotyrosine-immunoprecipitable PI3K (antiPTyr-PI3K) activity within 2 min in
L Evans et al.
The American journal of physiology, 272(2 Pt 1), C650-C656 (1997-02-01)
Confluent bovine aortic endothelial cells (EC) were grown on flexible membranes and subjected to 10% average strain at 60 cycles/min for up to 500 s. A biphasic increase in diacylglycerol (DAG) occurred, with an initial transient peak at 10 s
L Raptis et al.
Journal of virology, 63(2), 753-758 (1989-02-01)
Polyomavirus middle tumor antigen (mT) was expressed in a line of mouse NIH 3T3 cells under control of the dexamethasone-regulatable mouse mammary tumor virus promotor. Contrary to rat F111 cells which were rendered anchorage independent by mT expression alone (L.

商品

Discover Bioactive Small Molecules for Lipid Signaling Research

实验方案

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

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