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Merck
CN

P2533

聚-L-鸟氨酸 盐酸盐

suitable for ligand binding assays, Mol wt 15,000-30,000

别名:

L-Ornithine homopolymer hydrochloride

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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产品名称

聚-L-鸟氨酸 盐酸盐, mol wt 15,000-30,000

InChI key

GGTYBZJRPHEQDG-UHFFFAOYSA-N

SMILES string

Cl.NCCCC(N)C(O)=O

form

powder or solid

mol wt

15,000-30,000

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

Quality Level

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Analysis Note

分子量基于粘度。

Other Notes

有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源

Application

Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.

Biochem/physiol Actions

Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Adriana Di Polo, Leonard A. Levin
Ocular Neuroprotection (2003)
Hierarchical Structure Formation of Cylindrical Brush Polymer?Surfactant Complexes
Cong, Y. et al.
Langmuir, 25, 6392-6397 (2005)
Kun Luo et al.
Journal of integrative neuroscience, 20(3), 529-539 (2021-10-15)
Rab3a, a subtype protein in the Rab3 family amongst the small G proteins, is closely associated with the learning and memory formation process. Various neuronal stimuli can induce the expression of Rab3a; however, how DNA modification is involved in regulating
Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer
Yusuke K
Biologicals : Journal of the International Association of Biological Standardization (2017)
Use of Substrate Analogs and Mutagenesis to Study Substrate Binding and Catalysis in the Sir2 Family of NAD-dependent Protein Deacetylases*
Ahlia N
The Journal of Biological Chemistry (2006)

商品

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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