产品名称
聚-L-鸟氨酸 盐酸盐, mol wt 15,000-30,000
InChI key
GGTYBZJRPHEQDG-UHFFFAOYSA-N
SMILES string
Cl.NCCCC(N)C(O)=O
form
powder or solid
mol wt
15,000-30,000
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
Quality Level
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Analysis Note
分子量基于粘度。
Other Notes
有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源。
Application
Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.
Biochem/physiol Actions
Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Adriana Di Polo, Leonard A. Levin
Ocular Neuroprotection (2003)
Hierarchical Structure Formation of Cylindrical Brush Polymer?Surfactant Complexes
Cong, Y. et al.
Langmuir, 25, 6392-6397 (2005)
Kun Luo et al.
Journal of integrative neuroscience, 20(3), 529-539 (2021-10-15)
Rab3a, a subtype protein in the Rab3 family amongst the small G proteins, is closely associated with the learning and memory formation process. Various neuronal stimuli can induce the expression of Rab3a; however, how DNA modification is involved in regulating
Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer
Yusuke K
Biologicals : Journal of the International Association of Biological Standardization (2017)
Use of Substrate Analogs and Mutagenesis to Study Substrate Binding and Catalysis in the Sir2 Family of NAD-dependent Protein Deacetylases*
Ahlia N
The Journal of Biological Chemistry (2006)
商品
Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.
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