P2534
聚-L-组氨酸 盐酸盐
mol wt ≥5000
别名:
L-Histidine homopolymer hydrochloride
产品名称
聚-L-组氨酸 盐酸盐, mol wt ≥5000
InChI key
HNDVDQJCIGZPNO-RXMQYKEDSA-N
SMILES string
N[C@H](Cc1c[nH]cn1)C(O)=O
form
powder
mol wt
≥5000
color
white to very light yellow
storage temp.
−20°C
Quality Level
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Analysis Note
分子量 (MALLS)。
Other Notes
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J M Benns et al.
Bioconjugate chemistry, 11(5), 637-645 (2000-09-20)
Advancing biotechnology spurs the development of new pharmaceutically engineered gene delivery vehicles. Poly(L-histidine) ¿PLH¿ has been shown to induce membrane fusion at endosomal pH values, whereas PLL has a well documented efficacy in polyplex formation. Therefore, N-Ac-poly(L-histidine)-graft-poly(L-lysine) ¿PLH-g-PLL¿ was synthesized
Pablo R Dalmasso et al.
Analytica chimica acta, 710, 58-64 (2011-11-30)
We report for the first time the use of polyhistidine (Polyhis) to efficiently disperse multiwall carbon nanotubes (MWCNTs). The optimum dispersion MWCNT-Polyhis was obtained by sonicating for 30 min 1.0 mg mL(-1) MWCNTs in 0.25 mg mL(-1) Polyhis solution prepared
Carboxymethyl poly(L-histidine) as a new pH-sensitive polypeptide to enhance polyplex gene delivery.
Asayama S, Sudo M, et al.
Molecular Pharmacology, 5, 898-901 (2008)
商品
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