P259
1-O-Palmityl-sn-glycero-3-phosphocholine
powder
别名:
1-Hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Lysophosphatidylcholine, 1-hexadecyl, Lyso-PAF-C16, Lyso-platelet activating factor
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C24H52NO6P
化学文摘社编号:
分子量:
481.65
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
powder
color
white
solubility
H2O: 20 mg/mL
storage temp.
−20°C
SMILES string
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCC
InChI
1S/C24H52NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h24,26H,5-23H2,1-4H3/t24-/m1/s1
InChI key
VLBPIWYTPAXCFJ-XMMPIXPASA-N
Application
1-O-Palmityl-sn-glycero-3-phosphocholine also known as Lyso-PAF-(C16) can be used as a standard in the assay of platelet-activating factor.
Biochem/physiol Actions
Accumulation of lyso-PAF in atherogenic aortas may lead to unregulated PAF formation and can cause atherosclerosis.
Preparation Note
20mg of 1-O-Palmityl-sn-glycero-3-phosphocholine dissolves in 1 ml of water.
Other Notes
Inactive form of PAF[C16]
Disclaimer
Hygroscopic
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
G Montrucchio et al.
The American journal of pathology, 153(5), 1589-1596 (1998-11-12)
This study investigated the presence of platelet-activating factor (PAF) in the lipid extracts of 18 primary breast carcinomas and 20 control breast tissues. The amount of PAF detected in breast carcinomas was significantly higher than in controls. The mass spectrometric
C G Qian et al.
Journal of lipid mediators, 1(2), 113-123 (1989-03-01)
Suspensions of neonatal rat myocytes were used to investigate the metabolism of [3H]PAF (1-alkyl-2-acetyl-(sn-glycero-3-phosphocholine) (GPC] and [3H]alkyllyso-GPC. [3H]Alkylacyl-GPC consisting of molecular species with four or more double bonds (87%) was the major metabolite formed when either [3H]PAF (4 x 10(-6)
J X Kang et al.
The Biochemical journal, 303 ( Pt 3), 795-802 (1994-11-01)
Radioligand-binding studies were performed in primary cultured human airway epithelial cells with [3H]PAF to determine whether these cells express platelet-activating factor (PAF) receptors. Scatchard analysis of PAF binding data revealed a single class of PAF binding sites with Kd 1.8