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Merck
CN

P2658

聚-L-赖氨酸 盐酸盐

suitable for cell culture, Mol wt 15,000-30,000

别名:

L-Lysine hydrochloride homopolymer

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化学文摘社编号:
26124-78-7
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26
MDL number:
MFCD00081870

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产品名称

聚-L-赖氨酸 盐酸盐, mol wt 15,000-30,000

form

powder or solid

mol wt

15,000-30,000

technique(s)

cell culture | mammalian: suitable

color

white to light yellow

application(s)

cell analysis

storage temp.

−20°C

Quality Level

200

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Analysis Note

分子量基于粘度。

Application

分子量 >70,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
聚赖氨酸盐酸盐已被用于涂覆载玻片和盖玻片，以促进细胞附着。

Biochem/physiol Actions

一般认为赖氨酸可以预防骨质疏松症，骨质疏松症是血管钙化的一个特征。戊二酸尿症ⅰ型和吡哆醇依赖性癫痫的发生是由于缺乏赖氨酸分解代谢途径。赖氨酸参与一氧化氮合成的调节。它具有抗病毒活性，因此用于治疗单纯疱疹。赖氨酸与许多生化反应有关，如乙酰化、O-连接的糖基化、泛素化和蛋白质甲基化。一般认为聚赖氨酸是一种生物相容性聚合物，用于跨细胞膜给药。它可用作磁共振成像中的纳米造影剂之一。

Other Notes

有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000479587
0000479588
0000479587
0000479588
0000478649

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Mahesh Sahare et al.
Reproduction, fertility, and development, 28(12), 2039-2050 (2015-07-17)
Spermatogonial stem cells (SSCs) are unipotent in nature, but mouse SSCs acquire pluripotency under the appropriate culture conditions. Although culture systems are available for rodent and human germ-cell lines, no proven culture system is yet available for livestock species. Here
Archishman Ghosh et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(39), 19474-19483 (2019-09-12)
Membraneless organelles, corresponding to the droplet phase upon liquid-liquid phase separation (LLPS) of protein or protein-RNA mixtures, mediate myriad cellular functions. Cells use a variety of biochemical signals such as expression level and posttranslational modification to regulate droplet formation and
Multi-technique characterization of poly-L-lysine dendrigrafts-Cu(II) complexes for biocatalysis.
Rossi JC
Macromolecular Bioscience, 15(2), 275-290 (2015)
The role of signaling pathways on proliferation and self-renewal of cultured bovine primitive germ cells
Sahare Mahesh
Reproductive medicine and biology, 14(1) (2015)
Primary culture of neural precursors from the ovine central nervous system (CNS)
A. H. Duitozz and T. Hevor
Journal of Neuroscience Methods, 131-140 (2001)
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