生物来源
human
质量水平
重组
expressed in E. coli
方案
>95% (SDS-PAGE)
表单
solution
分子量
~31 kDa
apparent mol wt ~27 kDa
运输
dry ice
储存温度
−70°C
基因信息
human ... PPP1R1A(5502), PPP1R8(5511)
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应用
此蛋白磷酸酶抑制剂1适合用作底物,以鉴定调节蛋白磷酸酶抑制剂1活性的新型磷酸酶和激酶。该产品也适用于亲和力敲低结合研究。蛋白磷酸酶抑制剂1人已被用作蔗糖细胞裂解缓冲液中的一种成分。在药理学干预研究中,在腹膜前或腹膜内注射之前,它还被用于对小鼠进行腹膜内注射。
生化/生理作用
该酶作为磷酸化酶磷酸酶的抑制剂密切参与糖原代谢,负责将磷酸化酶 b转换为磷酸化酶 a。仅在cAMP依赖性蛋白激酶磷酸化时,才会激活抑制作用。
外形
以pH 7.0,含 50mM Tris-HCl、0.1 mM PMSF、14 mM 2-巯基乙醇和10%甘油的溶液形式提供
警示用语:
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
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