产品名称
多聚-L-赖氨酸，琥珀酰化, mol wt >50,000
form
powder or solid
mol wt
>50,000
color
white to faint yellow
application(s)
cell analysis
storage temp.
−20°C
Quality Level
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Analysis Note
分子量基于前体聚-L-赖氨酸的粘度。还通过MALLS被检测。
Application
琥珀酰化聚-L-赖氨酸已用于结合 (Gly)3-Arg-缓激肽，用于研究脑内肽酶和胰蛋白酶对其的水解。
Biochem/physiol Actions
聚-L-赖氨酸是一种阳离子聚合物。它主要用于将细胞固定在玻璃基板或带负电的基板上。
蛋白质与聚-L-赖氨酸偶联的中间体。
Other Notes
如需有关聚氨基酸的更多技术信息，请访问聚氨基酸常见问题解答资源。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Sofia Helena Linnea Frost et al.
Cancer biotherapy & radiopharmaceuticals, 26(6), 727-736 (2011-11-18)
Avidin-coupled monoclonal antibody MX35 (avidin-MX35) and astatine-211-labeled, biotinylated, succinylated poly-l-lysine ((211)At-B-PL(suc)) were administered in mice to assess potential efficacy as an intraperitoneal (i.p.) therapy for microscopic tumors. We aimed to establish a timeline for pretargeted radioimmunotherapy using these substances, and
Effects of poly(L-lysine) substrates on attached Escherichia coli bacteria.
Colville K
Langmuir, 26(4), 2639-2644 (2010)
V S Trubetskoy et al.
Nucleic acids research, 27(15), 3090-3095 (1999-08-24)
DNA can be condensed with an excess of poly-cations in aqueous solutions forming stable particles of submicron size with positive surface charge. This charge surplus can be used to deposit alternating layers of polyanions and polycations on the surface surrounding
Topographical Pattern Dynamics in Passive Adhesion of Cell Membranes
Alina Hategan
Biophysical Journal, 87(5), 3547?3560-3547?3560 (2004)
M R Hamblin et al.
British journal of cancer, 89(5), 937-943 (2003-08-28)
Conjugates between photosensitisers (PS) and charged polymeric carriers are under investigation for photodynamic therapy of cancer and may allow targeting to certain cell types or compartments in tumours. Covalent attachment of polyethylene glycol to macromolecules (pegylation) may alter their pharmacokinetics
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