P3591
1,2-二辛基- 锡 -甘油 3-磷酸 钠盐
≥99%
别名:
L-α-磷脂酸，二辛酰 钠盐
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关于此项目
线性分子式:
C19H36O8PNa
化学文摘社编号:
分子量:
446.45
NACRES:
NA.77
UNSPSC Code:
12352202
MDL number:
InChI
1S/C19H37O8P.Na/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2;/h17H,3-16H2,1-2H3,(H2,22,23,24);/q;+1/p-1/t17-;/m1./s1
InChI key
ZNDNSOYDPUTHKQ-UNTBIKODSA-M
assay
≥99%
form
powder
storage temp.
−20°C
General description
1,2-二辛酰基-sn-甘油3-磷酸钠盐是一种细胞渗透性磷脂酸（PA）。
Application
1,2-二辛酰基-sn-甘油 3-酸钠盐已被用于：
- 研究其对神经干/前体细胞（NSC）增殖的影响
- 研究磷脂酸（PA）对拟南芥表皮叶细胞肌动蛋白丝动力学的影响
- 处理载体转染的细胞，并验证丁醇对磷脂酶D（PLD）转染的细胞中缺氧诱导因子-1α（HIF-1α）诱导的减弱作用
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Yuko Fujita et al.
Biochemical and biophysical research communications, 370(1), 169-173 (2008-03-25)
While a mother's excessive alcohol consumption during pregnancy is known to have adverse effects on fetal neural development, little is known about the underlying mechanism of these effects. In order to investigate these mechanisms, we investigated the toxic effect of
Jindřiška Matoušková et al.
Plant science : an international journal of experimental plant biology, 223, 36-44 (2014-04-29)
Changes in actin cytoskeleton dynamics are one of the crucial players in many physiological as well as non-physiological processes in plant cells. Positioning of actin filament arrays is necessary for successful establishment of primary lines of defense toward pathogen attack
Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid
Han S, et al.
Experimental & Molecular Medicine, 46(12), e126-e126 (2014)
ETOH inhibits embryonic neural stem/precursor cell proliferation via PLD signaling
Fujita Y, et al.
Biochemical and Biophysical Research Communications, 370(1), 169-173 (2008)
Songyi Han et al.
Experimental & molecular medicine, 46, e126-e126 (2014-12-20)
Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is believed to play an important role in tumorigenesis. In this
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