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线性分子式:
CH3COCOONa
化学文摘社编号:
分子量:
110.04
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
204-024-4
Beilstein/REAXYS Number:
3568341
MDL number:
产品名称
丙酮酸钠, Hybri-Max™, powder, suitable for hybridoma
InChI key
DAEPDZWVDSPTHF-UHFFFAOYSA-M
InChI
1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
SMILES string
[Na+].CC(=O)C([O-])=O
biological source
synthetic (organic)
grade
Hybri-Max™
assay
≥99%
form
powder
technique(s)
cell culture | hybridoma: suitable
impurities
endotoxin, tested
mp
>300 °C (lit.)
solubility
H2O: 100 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
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Application
丙酮酸钠已被用作卵母细胞熟化培养基中的一种成分。
细胞利用丙酮酸钠作为一种易于获取的碳水化合物来源。此外,它参与氨基酸代谢,并启动Kreb循环。对于大多数细胞培养应用,100mM溶液应按1:100的比例进行稀释。
Biochem/physiol Actions
已知丙酮酸钠是以高氨血症为特征的II型瓜氨酸血症的一种有效治疗靶标。 体内研究证明,丙酮酸钠可通过防止脂质过氧化、NAD+还原和聚(ADP-核糖)聚合酶裂解而对出血性休克具有保护性功能。丙酮酸钠也已知具有抗炎作用,并可能会改善慢性肺部疾病。
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1B
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Metabolic and histologic effects of sodium pyruvate treatment in the rat after cortical contusion injury
Fukushima M, et al.
Journal of Neurotrauma, 26(7), 1095-1110 (2009)
Developmental competence and mRNA expression of preimplantation in vitro-produced embryos from prepubertal and postpubertal cattle and their relationship with apoptosis after intraovarian administration of IGF-1
Zaraza J, et al.
Theriogenology, 74(1), 75-89 (2010)
Characterisation of low, medium and high responders following FSH stimulation prior to ultrasound-guided transvaginal oocyte retrieval in cows
De RR, et al.
Animal Reproduction Science, 63(7), 1902-1913 (2005)
Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate
Mutoh K, et al.
Journal of inherited metabolic disease, 31(2), 343-347 (2008)
Essence of Anesthesia Practice: Expert Consult-Online and Print, 685-685 (2010)
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