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线性分子式:
CH3COCOONa
化学文摘社编号:
分子量:
110.04
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
204-024-4
Beilstein/REAXYS Number:
3568341
MDL number:
产品名称
丙酮酸钠, Hybri-Max™, powder, suitable for hybridoma
InChI key
DAEPDZWVDSPTHF-UHFFFAOYSA-M
InChI
1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
SMILES string
[Na+].CC(=O)C([O-])=O
biological source
synthetic (organic)
grade
Hybri-Max™
assay
≥99%
form
powder
technique(s)
cell culture | hybridoma: suitable
impurities
endotoxin, tested
mp
>300 °C (lit.)
solubility
H2O: 100 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
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Application
丙酮酸钠已被用作卵母细胞熟化培养基中的一种成分。
细胞利用丙酮酸钠作为一种易于获取的碳水化合物来源。此外,它参与氨基酸代谢,并启动Kreb循环。对于大多数细胞培养应用,100mM溶液应按1:100的比例进行稀释。
Biochem/physiol Actions
已知丙酮酸钠是以高氨血症为特征的II型瓜氨酸血症的一种有效治疗靶标。 体内研究证明,丙酮酸钠可通过防止脂质过氧化、NAD+还原和聚(ADP-核糖)聚合酶裂解而对出血性休克具有保护性功能。丙酮酸钠也已知具有抗炎作用,并可能会改善慢性肺部疾病。
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1B
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Developmental competence and mRNA expression of preimplantation in vitro-produced embryos from prepubertal and postpubertal cattle and their relationship with apoptosis after intraovarian administration of IGF-1
Zaraza J, et al.
Theriogenology, 74(1), 75-89 (2010)
Characterisation of low, medium and high responders following FSH stimulation prior to ultrasound-guided transvaginal oocyte retrieval in cows
De RR, et al.
Animal Reproduction Science, 63(7), 1902-1913 (2005)
Metabolic and histologic effects of sodium pyruvate treatment in the rat after cortical contusion injury
Fukushima M, et al.
Journal of Neurotrauma, 26(7), 1095-1110 (2009)
Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate
Mutoh K, et al.
Journal of inherited metabolic disease, 31(2), 343-347 (2008)
Essence of Anesthesia Practice: Expert Consult-Online and Print, 685-685 (2010)
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