P3738
Protein Kinase G Iβ human
≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, buffered aqueous glycerol solution
别名:
cyclic-Guanosine Monophosphate-dependent Protein Kinase 1β human
重组
expressed in baculovirus infected Sf9 cells
质量水平
方案
≥95% (SDS-PAGE)
表单
buffered aqueous glycerol solution
比活
≥1.5 units/mg protein (20-fold stimulation by cGMP (5 μM))
分子量
76 kDa (monomer)
UniProt登记号
相关疾病
cancer
运输
wet ice
储存温度
−20°C
基因信息
human ... PRKG1(5592)
应用
Protein Kinase G is a serine/threonine-specific protein kinase that is activated by cGMP. Protein Kinase G Iβ is used to induce apoptosis and inhibit cell proliferation.
生化/生理作用
Protein Kinase G Iβ induces apoptosis in certain cell lines such as human breast cancer cell lines MCF-7 and MDA-MB-468. It inhibits cell proliferation and induces apoptosis in colon cancer cell lines.
外形
Solution in 20 mM Tris buffer, pH 7.4, 1 mM EDTA, 1 mM β-mercaptoethanol, 100 mM NaCl, 10 U/ml Trasylol, and 50% glycerol.
其他说明
One unit will phosphorylate 1 micromole of VASPtide(RRKVSKQE) substrate per minute in 10 mM HEPES, pH 7.4, 5 mM MgCl2, 1 mM DTE and 0.2 mM EDTA.
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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