P3921
Parathyroid Hormone Fragment 1-34 rat
≥97% (HPLC), powder
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关于此项目
经验公式（希尔记法）:
C180H291N55O48S2
化学文摘社编号:
分子量:
4057.71
MDL编号:
UNSPSC代码:
51111800
NACRES:
NA.32
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Amino Acid Sequence
Ala-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-leu-Ala-Ser-Val-Glu-Arg-Met-Gln-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe
应用
Parathyroid Hormone Fragment 1-34 rat has been used to study the in vivo effect of parathyroid hormone (PTH) on the intestinal HCO3-secretion in rats. It has also been injected into rats to increase PTH levels and study its effect on the high-phosphate diet-induced elevation of blood pressure.
生化/生理作用
Parathyroid Hormone Fragment 1-34 is a parathyroid hormone (PTH) analog. It is implicated in the stimulation of intracellular cAMP accumulation and it induces osteocalcin (OC) promoter activity.
其他说明
Lyophilized from 0.1% TFA in H2O
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Narattaphol Charoenphandhu et al.
Biochemical and biophysical research communications, 409(4), 775-779 (2011-05-31)
Parathyroid hormone (PTH) was recently demonstrated to enhance the HCO(3)(-) secretion through the apical anion channel, cystic fibrosis transmembrane conductance regulator (CFTR), but how the HCO(3)(-) entered the epithelial cells was not well understood, in part, due to the lack
X P Yu et al.
Endocrinology, 138(8), 3085-3092 (1997-08-01)
Osteocalcin (OC) is a bone-specific extracellular matrix protein expressed by mature osteoblasts during late stages of differentiation. Previous studies have shown that forskolin, an activator of adenylate cyclase, stimulated OC production. Because PTH has been shown to activate several intracellular
Milica Bozic et al.
Journal of hypertension, 32(9), 1822-1832 (2014-07-01)
There is growing evidence suggesting that phosphate intake is associated with blood pressure levels. However, data from epidemiological studies show inconsistent results. The present study was designed to evaluate the effect of high circulating phosphorus on arterial blood pressure of
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