产品名称
精蛋白 来源于鲑鱼, Grade IV, Histone, free(Millon test)
biological source
fish (salmon)
type
Grade IV
form
solid
impurities
Histone, free (Millon test)
solubility
H2O: soluble, clear to slightly hazy, colorless to faintly yellow
storage temp.
−20°C
Quality Level
Application
鲑鱼中的鱼精蛋白已被用于在经肝素预处理的狗的样品中，以避免体外AT复合物的形成。它还已被用于研究外部电势对多种蛋白质在金属表面吸附的影响。
Biochem/physiol Actions
以固体脂质纳米粒 (SLN) 形式存在的鱼精蛋白促进质粒 DNA 转染的效率和细胞毒性低于由 Esterquat-1 组成的类似 SLN。
在动植物中，精蛋白被发现在生精过程中可置换DNA中的组蛋白。在心脏手术、透析和许多其他临床操作中，鱼精蛋白可用作肝素中和剂。
General description
鱼精蛋白是一种富含半胱氨酸和精氨酸的蛋白质。它具有多个磷酸化位点。鲑鱼含有大约15个编码鱼精蛋白的基因。它位于精子头部。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin
Petersen LC, et al.
British Journal of Haematology, 152(1), 99-107 (2011)
Ryan B McMillan et al.
Biophysical journal, 120(12), 2521-2531 (2021-05-24)
DNA looping plays an important role in cells in both regulating and protecting the genome. Often, studies of looping focus on looping by prokaryotic transcription factors like lac repressor or by structural maintenance of chromosomes proteins such as condensin. Here
Adsorption characteristics of various proteins on a metal surface in the presence of an external electric potential
Htwe EE, et al.
Colloids and Surfaces, B: Biointerfaces, 262-268 (2018)
Vanesa Lafarga et al.
The EMBO journal, 40(13), e103311-e103311 (2021-05-13)
Due to their capability to transport chemicals or proteins into target cells, cell-penetrating peptides (CPPs) are being developed as therapy delivery tools. However, and despite their interesting properties, arginine-rich CPPs often show toxicity for reasons that remain poorly understood. Using
Protamine and protamine reactions
Park Kyung W
International Anesthesiology Clinics, 42(3), 135-145 (2004)
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