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Merck
CN

P4154

聚肌苷酸 钾盐

Homopolymer

别名:

聚(I) 钾盐

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关于此项目

化学文摘社编号:
UNSPSC Code:
41106305
NACRES:
NA.51
MDL number:
Assay:
≥98% (TLC)
Biological source:
synthetic (organic)
Form:
lyophilized powder
Solubility:
water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow
Storage temp.:
−20°C
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biological source

synthetic (organic)

Quality Level

assay

≥98% (TLC)

form

lyophilized powder

solubility

water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow

storage temp.

−20°C

Application

聚肌苷酸(聚(I))是一种肌苷的均聚物,其可与聚胞苷酸(聚(C))一起形成双链均聚物(聚(I)·聚(C))。 TLR3 识别双链 RNA,并且是针对病毒病原体的免疫应答的主要效应分子。(Poly(I)•Poly(C))被用作研究 TLR3 水平的细胞信号传导的模型 RNA。Poly(IC)是一种 TRIF 依赖性 toll 样受体-3(TLR3)配体。

Preparation Note

通过多核苷酸磷酸化酶法从 IDP 制备。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gennady Dvoryanchikov et al.
Nature communications, 8(1), 760-760 (2017-10-04)
Taste buds are innervated by neurons whose cell bodies reside in cranial sensory ganglia. Studies on the functional properties and connectivity of these neurons are hindered by the lack of markers to define their molecular identities and classes. The mouse
Xingbo Wang et al.
Veterinary microbiology, 251, 108895-108895 (2020-10-31)
RNA binding ability and cellular distribution are important for nonstructural protein 1 (NS1) of influenza A virus to act as a viral regulatory factor to control virus life cycle. In this study, we identified that the N-terminal residues 19-21 of
Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo.
Packiriswamy N, Parvataneni S, Parameswaran N.
Cellular Immunology, 107-111 (2011)



全球贸易项目编号

货号GTIN
P4154-100MG04061834373612
P4154-10MG04061834373629
P4154-25MG04061833289921