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Merck
CN

P4354

Monoclonal Anti-p19INK4d antibody produced in mouse

clone DCS-100, ascites fluid

别名:

Anti-INK4D, Anti-p19, Anti-p19-INK4D

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
DCS-100, monoclonal
Application:
ARR, ICC, IHC (p), IP, WB
Citations:
3
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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

DCS-100, monoclonal

mol wt

antigen 19 kDa

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1:1,000 using a cultured human tumor cell line extract

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDKN2D(1032)

General description

Cyclin dependent kinase inhibitor 2D (CDKN2D), also referred to as p19INK4d, is part of the inhibitors of cyclin-dependent kinases (INK4) family. It consists of 166 amino acids and five ankyrin-like repeats that aid in protein-protein interactions. The gene encoding this protein is localized on human chromosome 19p13.

Immunogen

recombinant human p19INK4d.

Application

Monoclonal Anti-p19INK4d antibody produced in mouse has been used in microarray.

Biochem/physiol Actions

Cyclin dependent kinase inhibitor 2D (CDKN2D) functions as a modulator of the cell cycle and has a role in DNA damage response. It acts as a chromatin accessibility factor. The protein associates with cyclin-dependent kinase 4 and 6 and inhibits their kinase activity.
Shows no cross-reactivity with other closely related Cdk inhibitors, such as p15INK4b, p16INK4a and p18INK4c.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

动物来源生物产品
常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容


Further intracellular proteins and signaling pathways regulated by angiotensin-(1?7) in human endothelial cells
Christian Meinert
Data in Brief (2017)
Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation.
Sonzogni SV
Molecular and Cellular Biochemistry (2015)
Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation.
Anna F
Cancer Biology & Therapy (2013)



全球贸易项目编号

货号GTIN
P4354-.2ML04061837868320