P4354
Monoclonal Anti-p19INK4d antibody produced in mouse
clone DCS-100, ascites fluid
别名:
Anti-INK4D, Anti-p19, Anti-p19-INK4D
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关于此项目
Conjugate:
unconjugated
Clone:
DCS-100, monoclonal
Application:
ARR, ICC, IHC (p), IP, WB
Citations:
3
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
DCS-100, monoclonal
mol wt
antigen 19 kDa
contains
15 mM sodium azide
species reactivity
human
technique(s)
immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1:1,000 using a cultured human tumor cell line extract
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CDKN2D(1032)
General description
Cyclin dependent kinase inhibitor 2D (CDKN2D), also referred to as p19INK4d, is part of the inhibitors of cyclin-dependent kinases (INK4) family. It consists of 166 amino acids and five ankyrin-like repeats that aid in protein-protein interactions. The gene encoding this protein is localized on human chromosome 19p13.
Immunogen
recombinant human p19INK4d.
Application
Monoclonal Anti-p19INK4d antibody produced in mouse has been used in microarray.
Biochem/physiol Actions
Cyclin dependent kinase inhibitor 2D (CDKN2D) functions as a modulator of the cell cycle and has a role in DNA damage response. It acts as a chromatin accessibility factor. The protein associates with cyclin-dependent kinase 4 and 6 and inhibits their kinase activity.
Shows no cross-reactivity with other closely related Cdk inhibitors, such as p15INK4b, p16INK4a and p18INK4c.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
动植物来源生物产品
常规特殊物品
此项目有
Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation.
Sonzogni SV
Molecular and Cellular Biochemistry (2015)
Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation.
Anna F
Cancer Biology & Therapy (2013)
Further intracellular proteins and signaling pathways regulated by angiotensin-(1?7) in human endothelial cells
Christian Meinert
Data in Brief (2017)
相关内容
Datasheet
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