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Merck
CN

P4562

丙酮酸钠

powder, BioXtra, suitable for mouse embryo cell culture

别名:

α酮基丙酸 钠盐, 2-氧代丙酸 钠盐, 丙酮酸 钠盐

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关于此项目

线性分子式:
CH3COCOONa
化学文摘社编号:
113-24-6
分子量:
110.04
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24898552
EC Number:
204-024-4
Beilstein/REAXYS Number:
3568341
MDL number:
MFCD00002586

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产品名称

丙酮酸钠, powder, BioXtra, suitable for mouse embryo cell culture

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

SMILES string

[Na+].CC(=O)C([O-])=O

product line

BioXtra

assay

≥99%

form

powder

technique(s)

cell culture | embryo: suitable

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

storage temp.

2-8°C

Quality Level

200

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相关类别

Application

丙酮酸钠可用于：
  • 作为精子培养Ca2+ + N三羟甲基甲胺基乙磺酸(TES)–NaCl溶液的补充剂
  • 作为TCM-199 hepes改良溶液的补充剂，用于卵丘卵母细胞复合体(COC′s)培养
  • 作为杜氏改良Eagle培养基(DMEM)补充剂，用于培养小鼠原代肝细胞(MPH)，并用于腹腔注射禁食小鼠进行葡萄糖生成评估

Biochem/physiol Actions

丙酮酸钠主要用作培养基和肉汤组分。丙酮酸钠的抗氧化和抗炎作用可用于治疗过敏性鼻炎。丙酮酸钠还能用作乳酸中毒治疗的新药。
细胞将丙酮酸钠作为一种易于获取的碳水化合物来源。此外，它还参与氨基酸代谢并启动Kreb′循环。丙酮酸钠减弱体外氧化应激。 对于大多数细胞培养应用，应将100 mM溶液按1:100比例稀释。 该产品已被认证可用于小鼠胚胎培养。

General description

丙酮酸盐(pyruvate)，糖酵解通路的终产物，是丙酮酸(pyruvic acid)的阴离子形式。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000512953
0000512953
0000500374
0000500374
0000495061

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In vitro maturation of caprine oocytes in different concentrations of estrous goat serum
Kharche SD, et al.
Small Ruminant Research (2006)
L S Li et al.
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 31(2), 103-106 (2017-01-20)
Objective:Pyruvate is a key intermediate in several metabolic pathways of human body Sodium pyruvate possesses anti-oxidation and anti-inflammatory effects, which make it a possible novel therapy for allergic rhinitis. However, the relevant clinical research is rare. The aim of the
Kyle S McCommis et al.
The Biochemical journal, 466(3), 443-454 (2015-03-10)
Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely
Jing Yang et al.
Artificial cells, nanomedicine, and biotechnology, 44(1), 48-55 (2014-04-05)
To examine the effects of sodium pyruvate (SP) on metabolic acidosis. For the in vivo experiments, we evaluated effects of SP on an ammonium chloride (NH4Cl)-induced hyperchloremic acidosis rat model. SP was infused at overall doses of 2, 4, and
Rangga Setiawan et al.
Animal reproduction science, 233, 106843-106843 (2021-09-15)
Adenosine triphosphate (ATP) production via glycolysis and oxidative phosphorylation is essential for the maintenance of flagellar motility in sperm; however, the primary energy production pathways supporting fertilization vary among species. Inconsistency in thought exists regarding which pathways maintain ATP production
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Product Information Sheet - P4562

Product Information Sheet

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