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About This Item
经验公式（希尔记法）:
C21H27NO3 · HCl
CAS Number:
分子量:
377.90
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.77
表单
powder
质量水平
创始人
Abbott
储存温度
2-8°C
SMILES字符串
Cl[H].CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2
InChI
1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H
InChI key
XWIHRGFIPXWGEF-UHFFFAOYSA-N
基因信息
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一般描述
Propafenone hydrochloride is a calcium antagonist. It functions as a Na+ and K+ channel blocker. It might be used to treat patients with systemic hypertension. Propafenone hydrochloride is associated with bradycardia and bronchospasms. It is metabolized in the liver. Propafenone hydrochloride is used to treat ventricular arrhythmias.
应用
Propafenone hydrochloride has been used in the isolation of cardiomyocytes.
生化/生理作用
Blocks hKv1.5 and ATP-sensitive K+ channels; class 1C antiarrhythmic agent that is also an antagonist at β adrenergic receptors.
特点和优势
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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