Application
聚(脱氧肌苷 - 脱氧胞苷)酸钠盐已用于p65蛋白和neuro-2A蛋白裂解物的电泳迁移位移试验。它还被用作蛋白精氨酸甲基转移酶1(PRMT1)和DNA甲基转移酶1(DNMT1)选择性测定中的底物。
聚(脱氧肌苷 - 脱氧胞苷)酸钠盐已用于合成和表征双(2-(嘧啶-2-γl)乙氧基)烷烃及其药理活性的研究中。聚(脱氧肌苷 - 脱氧胞苷)酸钠盐也已用于研究碳酸钙薄膜在LB/LbL基质上生长。
聚(脱氧肌苷-脱氧胞苷)酸(聚(dI-dC)•聚(dI-dC))是可用作DNA底物的交替共聚物,其可用于评估DNA甲基转移酶(如DNA甲基转移酶1),以及作为双链DNA模型用于DNA结构动力学和药物、小分子、相互作用的构象研究。
Biochem/physiol Actions
聚(2′-脱氧肌苷-2′-脱氧胞苷酸),聚(dI-dC)是一种合成的DNA底物。在高盐下,Poly(dI-dC)以左旋螺旋构象存在,并在降低盐浓度过程中恢复为右旋形式。它可用于电泳迁移位移试验(EMSA)。
Other Notes
双链交替共聚物
在20mM磷酸钠/100mMNaCl(pH 7.0)缓冲液中,一个单位可在1.0ml中产生A260 = 1.0(1cm光程)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Dimitrios Priftis et al.
Langmuir : the ACS journal of surfaces and colloids, 28(23), 8721-8729 (2012-05-15)
A systematic study of the interfacial energy (γ) of polypeptide complex coacervates in aqueous solution was performed using a surface forces apparatus (SFA). Poly(L-lysine hydrochloride) (PLys) and poly(L-glutamic acid sodium salt) (PGA) were investigated as a model pair of oppositely
Meaghan L Clark et al.
Inorganic chemistry, 47(20), 9410-9418 (2008-09-25)
This paper focuses on DNA-binding interactions exhibited by Pt(dma-T)CN(+), where dma-T denotes 4'-dimethylamino-2,2':6',2''-terpyridine, and includes complementary studies of the corresponding pyrr-T complex, where pyrr-T denotes 4'-(N-pyrrolidinyl)-2,2':6',2''-terpyridine. The chromophores are useful for understanding the interesting and rather intricate DNA-binding interactions exhibited
Dexamethasone treatment of calves latently infected with bovine herpesvirus 1 leads to activation of the bICP0 early promoter, in part by the cellular transcription factor C/EBP-alpha
Workman A, et al.
Journal of Virology, 83(17), 8800-8809 (2009)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P4929-25UN | 04061834375456 |
| P4929-5UN | 04061834375463 |
| P4929-10UN | 04061834375432 |