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Merck
CN

P5069

Sigma-Aldrich

前列腺素F2Α氨丁三醇盐α 三羟甲基氨基甲烷盐

synthetic, suitable for cell culture

别名:

(5Z,9α,11α,13E,15S)-9,11,15-三羟基前列腺-5,13-二烯酸 三羟甲基氨基甲烷盐, 前列腺素 f −Tris

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关于此项目

经验公式(希尔记法):
C20H34O5 · C4H11NO3
化学文摘社编号:
分子量:
475.62
Beilstein:
4087514
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.77
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生物来源

synthetic

质量水平

方案

≥99%

表单

powder

技术

cell culture | mammalian: suitable

溶解性

ethanol: 50 mg/mL, clear, colorless

运输

ambient

储存温度

−20°C

SMILES字符串

NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC

InChI

1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1

InChI key

IYGXEHDCSOYNKY-RZHHZEQLSA-N

基因信息

human ... PTGFR(5737)

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生化/生理作用

前列腺素 F2α由子宫产生的催产素诱导,作用于黄体引起黄体溶解,抑制孕酮生成。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。也可刺激平滑肌(如支气管)收缩,可能与哮喘有关。这种作用至少部分通过速激肽释放介导。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。子宫内膜 PG F 2α 之间的正反馈环黄体溶解由黄体催产素完成

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Physiological reports, 3(4) (2015-04-17)
Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section. We investigated the influence of maternal age on myometrial contractility, expression of contractile associated proteins (CAPs), and global
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Biochimica et biophysica acta, 1793(12), 1917-1928 (2009-10-13)
Pro-inflammatory mediators, like prostaglandin (PG) and chemokines, promote tumourigenesis by enhancing cell proliferation, migration of immune cells and recruitment of blood vessels. Recently we showed elevated expression of the chemokine (C-X-C motif) receptor 2 (CXCR2) in endometrial adenocarcinomas localized to
Nicole A Rapicavoli et al.
BMC developmental biology, 10, 49-49 (2010-05-13)
Recent work has identified that many long mRNA-like noncoding RNAs (lncRNAs) are expressed in the developing nervous system. Despite their abundance, the function of these ncRNAs has remained largely unexplored. We have investigated the highly abundant lncRNA RNCR2 in regulation
M Sarkar et al.
Reproduction in domestic animals = Zuchthygiene, 45(3), 393-398 (2009-09-09)
An attempt was undertaken to investigate the efficacy of Ovsynch protocol for timed artificial insemination (TAI) with or without Norprolac (antiprolactin) treatment during non-breeding season (winter months) in yaks (n = 25). During non-breeding season, plasma prolactin profile has been
J V Lopez et al.
The Veterinary record, 164(26), 807-809 (2009-06-30)
Twenty-four to 36 hours after farrowing, 192 sows were treated with a single intramuscular injection (2 ml per animal) of a prostaglandin analogue; 102 were treated with cloprostenol racemate and 97 with dinoprost tromethamine, and 90 were left untreated. There

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