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Merck
CN

P5069

前列腺素F2Α氨丁三醇盐α 三羟甲基氨基甲烷盐

synthetic, suitable for cell culture

别名:

(5Z,9α,11α,13E,15S）-9,11,15-三羟基前列腺-5,13-二烯酸 三羟甲基氨基甲烷盐, 前列腺素 f 2α−Tris

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关于此项目

经验公式（希尔记法）:
C20H34O5 · C4H11NO3
化学文摘社编号:
38562-01-5
分子量:
475.62
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
24898587
EC Number:
254-002-3
Beilstein/REAXYS Number:
4087514
MDL number:
MFCD00077863
Biological source:
synthetic
Form:
powder
Assay:
≥99%

主要文件

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产品名称

前列腺素F2Α氨丁三醇盐α 三羟甲基氨基甲烷盐, synthetic, suitable for cell culture

InChI key

IYGXEHDCSOYNKY-RZHHZEQLSA-N

InChI

1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1

SMILES string

NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC

biological source

synthetic

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

ethanol: 50 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

Quality Level

200

Gene Information

human ... PTGFR(5737)

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相关类别

Biochem/physiol Actions

前列腺素 F2α由子宫产生的催产素诱导，作用于黄体引起黄体溶解，抑制孕酮生成。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。也可刺激平滑肌（如支气管）收缩，可能与哮喘有关。这种作用至少部分通过速激肽释放介导。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。子宫内膜 PG F 2α 之间的正反馈环黄体溶解由黄体催产素完成 。

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000341879
0000341879
SLCP1320
SLCP1320
SLCN6711

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Matthew Elmes et al.
Physiological reports, 3(4) (2015-04-17)
Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section. We investigated the influence of maternal age on myometrial contractility, expression of contractile associated proteins (CAPs), and global
Daniel M Kozink et al.
Theriogenology, 58(5), 1039-1045 (2002-09-06)
The objective was to determine if i.m. treatments of lutalyse (PGF2alpha; dinoprost tromethamine salt) expedited the training of sexually inexperienced boars for semen collection. Lean-type, terminal-line boars (n = 40; 177.4 +/- 2.4 day of age and 112.8 +/- 2.0
Chafika Mazouni et al.
Contraception, 73(3), 244-248 (2006-02-14)
To evaluate the safety and efficacy of termination of pregnancy using mifepristone and misosprostol at more than 15 weeks' gestation in patients with uterine scar due to previous cesarean section. This retrospective study was conducted in a tertiary maternity ward
J R Pursley et al.
Theriogenology, 78(4), 823-829 (2012-05-26)
Using two PGF(2α) treatments 14 days apart as a way to enhance estrus detection rate following the 2nd treatment is a reproductive management tool that continues to be used on large dairy farms. In one study, in cows with a
J V Lopez et al.
The Veterinary record, 164(26), 807-809 (2009-06-30)
Twenty-four to 36 hours after farrowing, 192 sows were treated with a single intramuscular injection (2 ml per animal) of a prostaglandin analogue; 102 were treated with cloprostenol racemate and 97 with dinoprost tromethamine, and 90 were left untreated. There
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