P5386
Poly-γ-benzyl-L-glutamate
mol wt 70,000-150,000
别名:
PBLG
表单
powder
质量水平
分子量
70,000-150,000
颜色
white to light yellow
储存温度
−20°C
SMILES字符串
[N+H3][C@@H](CCC(=O)OCc1ccccc1)C(=O)[O-]
InChI
1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1
InChI key
BGGHCRNCRWQABU-JTQLQIEISA-N
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应用
- Hydrogen bond formation may enhance RDC-based discrimination of enantiomers.: This research explores the impact of hydrogen bond formation on residual dipolar couplings (RDC) in the discrimination of enantiomers. Poly-y-benzyl-L-glutamate (PBLG) is used as a chiral alignment medium, enhancing the sensitivity and resolution of NMR spectroscopy for enantiomeric analysis (Sager et al., 2024).
- Potential and performance of anisotropic (19)F NMR for the enantiomeric analysis of fluorinated chiral active pharmaceutical ingredients.: This study highlights the use of PBLG as an alignment medium in anisotropic 19F NMR spectroscopy for analyzing chiral pharmaceutical compounds. The research demonstrates improved enantiomeric discrimination and quantification, crucial for pharmaceutical development (Gouilleux et al., 2024).
- Block Sequence Effects on the Self-Assembly Behaviors of Polypeptide-Based Penta-Block Copolymer Hydrogels.: This study investigates the self-assembly behavior of block copolymer hydrogels containing PBLG. The research shows how block sequence affects the mechanical properties and potential applications of these hydrogels in biomedical fields (Wang et al., 2024).
- Liquid crystalline composite hydrogels with large pH-triggered anisotropic swelling for embolotherapy.: This research explores the development of liquid crystalline hydrogels incorporating PBLG for use in embolotherapy. The hydrogels demonstrate significant pH-responsive swelling, making them suitable for targeted medical applications (Zhang et al., 2024).
分析说明
分子量基于粘度。
其他说明
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Electrospun Poly(γ-Benzyl-l-Glutamate) and Its Alkali-Treated Meshes: Their Water Wettability and Cell-Adhesion Potential.
Hakamada Y, Ohgushi N, et al.
Journal of Biomaterials Science. Polymer Edition, 28(1), 757-765 (2011)
Kamal K Upadhyay et al.
Biomaterials, 31(10), 2882-2892 (2010-01-08)
We have investigated the intracellular delivery of doxorubicin (DOX) loaded poly(gamma-benzyl L-glutamate)-block-hyaluronan (PBLG-b-HYA) based polymersomes (PolyDOX) in high (MCF-7) and low (U87) CD44 expressing cancer cell models. DOX was successfully loaded into polymersomes using nanoprecipitation method and in vitro drug
Permanent polarity and piezoelectricity of electrospun α-helical poly(α-amino acid) fibers.
Dawnielle Farrar et al.
Advanced materials (Deerfield Beach, Fla.), 23(34), 3954-3958 (2011-07-29)
Thavasyappan Thambi et al.
Bioconjugate chemistry, 22(10), 1924-1931 (2011-09-09)
Poly(ethylene glycol)-b-poly(γ-benzyl L-glutamate)s bearing the disulfide bond (PEG-SS-PBLGs), which is specifically cleavable in intracellular compartments, were prepared via a facile synthetic route as a potential carrier of camptothecin (CPT). Diblock copolymers with different lengths of PBLG were synthesized by ring-opening
Christie Aroulanda et al.
The Journal of chemical physics, 134(13), 134502-134502 (2011-04-12)
Enantiotopic discrimination in the NMR spectra of prochiral rigid solutes in chiral liquid crystals (CLC), by the ordering mechanism, is limited to molecules possessing one of the four, so called, "allowed" symmetries, D(2d), C(2v), C(s), and S(4). So far, such
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